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The association of occupational asbestos dust exposure and laryngeal carcinoma.
Isr J Med Sci. 1995 Sep; 31(9):540-8.IJ

Abstract

Controversy exists as to whether occupational asbestos dust exposure is responsible, or at least partially responsible, for the development of laryngeal carcinoma. The aim of this study is to present the current scientific knowledge on this subject based on a comprehensive literature research and to critically review the epidemiological investigations published. The results of 31 cohort studies and 24 case-control studies, and the conclusions in 11 more recent reviews are contradictory. In most studies there was no statistically significant indication of a casual relationship. It is noteworthy that an increased risk of laryngeal carcinoma among persons exposed to asbestos dust was observed mostly in older studies in which smoking habits and/or alcohol consumption as the most important nonoccupational risk factors were usually not taken into account. In addition, since most of the calculated positive associations are very weak, no reliable conclusion can be reached. While there may be a causal relationship between occupational exposure to asbestos dust and the occurrence of laryngeal carcinoma, this cannot be regarded as certain on the basis of the evidence reviewed.

Authors+Show Affiliations

Institute for Occupational, Social and Environmental Medicine, University of Erlangen-Nuremberg, Germany.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

7558778

Citation

Kraus, T, et al. "The Association of Occupational Asbestos Dust Exposure and Laryngeal Carcinoma." Israel Journal of Medical Sciences, vol. 31, no. 9, 1995, pp. 540-8.
Kraus T, Drexler H, Weber A, et al. The association of occupational asbestos dust exposure and laryngeal carcinoma. Isr J Med Sci. 1995;31(9):540-8.
Kraus, T., Drexler, H., Weber, A., & Raithel, H. J. (1995). The association of occupational asbestos dust exposure and laryngeal carcinoma. Israel Journal of Medical Sciences, 31(9), 540-8.
Kraus T, et al. The Association of Occupational Asbestos Dust Exposure and Laryngeal Carcinoma. Isr J Med Sci. 1995;31(9):540-8. PubMed PMID: 7558778.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The association of occupational asbestos dust exposure and laryngeal carcinoma. AU - Kraus,T, AU - Drexler,H, AU - Weber,A, AU - Raithel,H J, PY - 1995/9/1/pubmed PY - 1995/9/1/medline PY - 1995/9/1/entrez SP - 540 EP - 8 JF - Israel journal of medical sciences JO - Isr. J. Med. Sci. VL - 31 IS - 9 N2 - Controversy exists as to whether occupational asbestos dust exposure is responsible, or at least partially responsible, for the development of laryngeal carcinoma. The aim of this study is to present the current scientific knowledge on this subject based on a comprehensive literature research and to critically review the epidemiological investigations published. The results of 31 cohort studies and 24 case-control studies, and the conclusions in 11 more recent reviews are contradictory. In most studies there was no statistically significant indication of a casual relationship. It is noteworthy that an increased risk of laryngeal carcinoma among persons exposed to asbestos dust was observed mostly in older studies in which smoking habits and/or alcohol consumption as the most important nonoccupational risk factors were usually not taken into account. In addition, since most of the calculated positive associations are very weak, no reliable conclusion can be reached. While there may be a causal relationship between occupational exposure to asbestos dust and the occurrence of laryngeal carcinoma, this cannot be regarded as certain on the basis of the evidence reviewed. SN - 0021-2180 UR - https://www.unboundmedicine.com/medline/citation/7558778/The_association_of_occupational_asbestos_dust_exposure_and_laryngeal_carcinoma_ L2 - https://medlineplus.gov/asbestos.html DB - PRIME DP - Unbound Medicine ER -