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Binswanger's disease presenting as levodopa-responsive parkinsonism: clinicopathologic study of three cases.
Mov Disord. 1995 Jul; 10(4):450-4.MD

Abstract

We report three cases of autopsy-proven Binswanger's disease (subcortical arteriosclerotic encephalopathy) with unusual clinical features. Two patients had supranuclear gaze disturbances, early gait dysfunction, and speech disorders suggestive of progressive supranuclear palsy. One of these patients was not demented at the time of death. The third patient had features typical of Parkinson's disease. All three patients were responsive to treatment with levodopa. The clinical spectrum of Binswanger's disease should be expanded to include levodopa-responsive parkinsonism.

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Authors+Show Affiliations

Mark MH
Department of Neurology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick 08903, USA.
Sage JI
No affiliation info available
Walters AS
No affiliation info available
Duvoisin RC
No affiliation info available
Miller DC
No affiliation info available

MeSH

AgedAtrophyBrainCerebral ArteriesDementia, Multi-InfarctFemaleHumansIntracranial ArteriosclerosisLevodopaMaleMiddle AgedNeurologic ExaminationParkinson DiseaseSupranuclear Palsy, Progressive

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

7565825

Citation

Mark, M H., et al. "Binswanger's Disease Presenting as Levodopa-responsive Parkinsonism: Clinicopathologic Study of Three Cases." Movement Disorders : Official Journal of the Movement Disorder Society, vol. 10, no. 4, 1995, pp. 450-4.
Mark MH, Sage JI, Walters AS, et al. Binswanger's disease presenting as levodopa-responsive parkinsonism: clinicopathologic study of three cases. Mov Disord. 1995;10(4):450-4.
Mark, M. H., Sage, J. I., Walters, A. S., Duvoisin, R. C., & Miller, D. C. (1995). Binswanger's disease presenting as levodopa-responsive parkinsonism: clinicopathologic study of three cases. Movement Disorders : Official Journal of the Movement Disorder Society, 10(4), 450-4.
Mark MH, et al. Binswanger's Disease Presenting as Levodopa-responsive Parkinsonism: Clinicopathologic Study of Three Cases. Mov Disord. 1995;10(4):450-4. PubMed PMID: 7565825.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Binswanger's disease presenting as levodopa-responsive parkinsonism: clinicopathologic study of three cases. AU - Mark,M H, AU - Sage,J I, AU - Walters,A S, AU - Duvoisin,R C, AU - Miller,D C, PY - 1995/7/1/pubmed PY - 1995/7/1/medline PY - 1995/7/1/entrez SP - 450 EP - 4 JF - Movement disorders : official journal of the Movement Disorder Society JO - Mov Disord VL - 10 IS - 4 N2 - We report three cases of autopsy-proven Binswanger's disease (subcortical arteriosclerotic encephalopathy) with unusual clinical features. Two patients had supranuclear gaze disturbances, early gait dysfunction, and speech disorders suggestive of progressive supranuclear palsy. One of these patients was not demented at the time of death. The third patient had features typical of Parkinson's disease. All three patients were responsive to treatment with levodopa. The clinical spectrum of Binswanger's disease should be expanded to include levodopa-responsive parkinsonism. SN - 0885-3185 UR - https://www.unboundmedicine.com/medline/citation/7565825/Binswanger's_disease_presenting_as_levodopa_responsive_parkinsonism:_clinicopathologic_study_of_three_cases_ L2 - https://doi.org/10.1002/mds.870100408 DB - PRIME DP - Unbound Medicine ER -