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Long-term adherence to intensified conventional insulin therapy.
Exp Clin Endocrinol Diabetes. 1995; 103(4):256-9.EC

Abstract

All diabetic patients of the outpatient clinic of the University of Frankfurt/Main, who started intensified conventional insulin therapy (ICT) between 1980 and 1991, and who could be followed for at least one year (n = 141) were evaluated retrospectively. Fourteen patients changed from ICT to continuous subcutaneous insulin infusion (CSII). No patient changed back permanently to conventional insulin therapy. Mean glycosylated hemoglobin-levels (HbA1) decreased significantly in the first year from 9.3% to 8.5% and remained at a near normal level in the following years. HbA1-levels were found not to be associated with age, age at diagnosis, weight gain, frequency of visits to the outpatient clinic, number of consultations with the dietician as well as the frequency of attendance at special seminars for ICT. These results demonstrate that ICT lowered blood glucose levels permanently, that patients were highly compliant, and that ICT was practicable and safe for long-term treatment under routine conditions without initial hospitalization and with an acceptable expenditure of time for patients and medical staff.

Authors+Show Affiliations

J. W. Goethe-University, School of Medicine, Department of Endocrinology, Frankfurt/Main.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article

Language

eng

PubMed ID

7584532

Citation

Schmidt, K, et al. "Long-term Adherence to Intensified Conventional Insulin Therapy." Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association, vol. 103, no. 4, 1995, pp. 256-9.
Schmidt K, Boehm BO, Schifferdecker E, et al. Long-term adherence to intensified conventional insulin therapy. Exp Clin Endocrinol Diabetes. 1995;103(4):256-9.
Schmidt, K., Boehm, B. O., Schifferdecker, E., & Usadel, K. H. (1995). Long-term adherence to intensified conventional insulin therapy. Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association, 103(4), 256-9.
Schmidt K, et al. Long-term Adherence to Intensified Conventional Insulin Therapy. Exp Clin Endocrinol Diabetes. 1995;103(4):256-9. PubMed PMID: 7584532.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Long-term adherence to intensified conventional insulin therapy. AU - Schmidt,K, AU - Boehm,B O, AU - Schifferdecker,E, AU - Usadel,K H, PY - 1995/1/1/pubmed PY - 1995/1/1/medline PY - 1995/1/1/entrez SP - 256 EP - 9 JF - Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association JO - Exp Clin Endocrinol Diabetes VL - 103 IS - 4 N2 - All diabetic patients of the outpatient clinic of the University of Frankfurt/Main, who started intensified conventional insulin therapy (ICT) between 1980 and 1991, and who could be followed for at least one year (n = 141) were evaluated retrospectively. Fourteen patients changed from ICT to continuous subcutaneous insulin infusion (CSII). No patient changed back permanently to conventional insulin therapy. Mean glycosylated hemoglobin-levels (HbA1) decreased significantly in the first year from 9.3% to 8.5% and remained at a near normal level in the following years. HbA1-levels were found not to be associated with age, age at diagnosis, weight gain, frequency of visits to the outpatient clinic, number of consultations with the dietician as well as the frequency of attendance at special seminars for ICT. These results demonstrate that ICT lowered blood glucose levels permanently, that patients were highly compliant, and that ICT was practicable and safe for long-term treatment under routine conditions without initial hospitalization and with an acceptable expenditure of time for patients and medical staff. SN - 0947-7349 UR - https://www.unboundmedicine.com/medline/citation/7584532/Long_term_adherence_to_intensified_conventional_insulin_therapy_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-0029-1211359 DB - PRIME DP - Unbound Medicine ER -