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Relapses during long-term follow up with drug-susceptible M. leprae among multibacillary leprosy patients treated with multidrug therapy regimens; case reports.
Int J Lepr Other Mycobact Dis. 1995 Sep; 63(3):391-4.IJ

Abstract

A controlled clinical trial in highly bacilliferous multibacillary leprosy patients was initiated in 1977. We report here two cases of relapse during long-term follow up of patients 15 years after the start of treatment. The patients reported here were treated with rifampin, isoniazid, clofazimine and dapsone for the first 3 months followed by clofazimine and dapsone until 84 months in one case; the other case received the same treatment but had received dapsone alone for 60-80 months. The relapses occurred 6(1/2) 7(1/2) years after therapy was discontinued.

Authors+Show Affiliations

Tuberculosis Research Centre, Madras, India.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Clinical Trial
Controlled Clinical Trial
Journal Article

Language

eng

PubMed ID

7594922

Citation

Thomas, A, et al. "Relapses During Long-term Follow Up With Drug-susceptible M. Leprae Among Multibacillary Leprosy Patients Treated With Multidrug Therapy Regimens; Case Reports." International Journal of Leprosy and Other Mycobacterial Diseases : Official Organ of the International Leprosy Association, vol. 63, no. 3, 1995, pp. 391-4.
Thomas A, Hari L, Nagarajan M, et al. Relapses during long-term follow up with drug-susceptible M. leprae among multibacillary leprosy patients treated with multidrug therapy regimens; case reports. Int J Lepr Other Mycobact Dis. 1995;63(3):391-4.
Thomas, A., Hari, L., Nagarajan, M., & Prabhakar, R. (1995). Relapses during long-term follow up with drug-susceptible M. leprae among multibacillary leprosy patients treated with multidrug therapy regimens; case reports. International Journal of Leprosy and Other Mycobacterial Diseases : Official Organ of the International Leprosy Association, 63(3), 391-4.
Thomas A, et al. Relapses During Long-term Follow Up With Drug-susceptible M. Leprae Among Multibacillary Leprosy Patients Treated With Multidrug Therapy Regimens; Case Reports. Int J Lepr Other Mycobact Dis. 1995;63(3):391-4. PubMed PMID: 7594922.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Relapses during long-term follow up with drug-susceptible M. leprae among multibacillary leprosy patients treated with multidrug therapy regimens; case reports. AU - Thomas,A, AU - Hari,L, AU - Nagarajan,M, AU - Prabhakar,R, PY - 1995/9/1/pubmed PY - 1995/9/1/medline PY - 1995/9/1/entrez SP - 391 EP - 4 JF - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association JO - Int J Lepr Other Mycobact Dis VL - 63 IS - 3 N2 - A controlled clinical trial in highly bacilliferous multibacillary leprosy patients was initiated in 1977. We report here two cases of relapse during long-term follow up of patients 15 years after the start of treatment. The patients reported here were treated with rifampin, isoniazid, clofazimine and dapsone for the first 3 months followed by clofazimine and dapsone until 84 months in one case; the other case received the same treatment but had received dapsone alone for 60-80 months. The relapses occurred 6(1/2) 7(1/2) years after therapy was discontinued. SN - 0148-916X UR - https://www.unboundmedicine.com/medline/citation/7594922/Relapses_during_long_term_follow_up_with_drug_susceptible_M__leprae_among_multibacillary_leprosy_patients_treated_with_multidrug_therapy_regimens DB - PRIME DP - Unbound Medicine ER -