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Distal splenorenal shunt for non-cirrhotic variceal bleeding in black South Africans.
S Afr J Surg. 1994 Sep; 32(3):87-90.SA

Abstract

Distal splenorenal shunt (DSRS) is a once-only form of treatment. It is suitable for many black South Africans with non-cirrhotic variceal bleeding who cannot attend repeated follow-up sclerotherapy sessions. However, persistent hyperbilirubinaemia and encephalopathy may occur following DSRS in schistosomiasis. Forty-one consecutive patients with DSRS have been treated over a 7-year period. The causes of portal hypertension were schistosomiasis (32), portal vein thrombosis (8) and diffuse nodular hyperplasia (1). Operative mortality was 6%. Encephalopathy was observed in 1 patient. Galactose elimination capacity (GEC) and technetium-diethylenetriamine penta-acetic acid hepatic perfusion index (HPI) were used to assess liver function and hepatic perfusion pre- and postoperatively, respectively, in schistosomiasis. GEC was 348 +/- 37 (M +/- SD) before, compared with 343 +/- 67 postoperatively (P = 0.78). HPI showed long-term preservation of hepatopetal portal venous flow following DSRS. Morbidity and mortality were observed only in patients with schistosomiasis associated with hepatitis B chronic active hepatitis. DSRS is ideal treatment in selected patients with non-cirrhotic variceal bleeding.

Authors+Show Affiliations

Department of Surgery, Medical University of Southern Africa, Pretoria.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

7597501

Citation

Modiba, M C., et al. "Distal Splenorenal Shunt for Non-cirrhotic Variceal Bleeding in Black South Africans." South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie, vol. 32, no. 3, 1994, pp. 87-90.
Modiba MC, Koto Z, Lowan TA, et al. Distal splenorenal shunt for non-cirrhotic variceal bleeding in black South Africans. S Afr J Surg. 1994;32(3):87-90.
Modiba, M. C., Koto, Z., Lowan, T. A., Magano, S., Segal, I., Esser, J., Pantanowitz, D., & Myburgh, J. A. (1994). Distal splenorenal shunt for non-cirrhotic variceal bleeding in black South Africans. South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie, 32(3), 87-90.
Modiba MC, et al. Distal Splenorenal Shunt for Non-cirrhotic Variceal Bleeding in Black South Africans. S Afr J Surg. 1994;32(3):87-90. PubMed PMID: 7597501.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Distal splenorenal shunt for non-cirrhotic variceal bleeding in black South Africans. AU - Modiba,M C, AU - Koto,Z, AU - Lowan,T A, AU - Magano,S, AU - Segal,I, AU - Esser,J, AU - Pantanowitz,D, AU - Myburgh,J A, PY - 1994/9/1/pubmed PY - 1994/9/1/medline PY - 1994/9/1/entrez SP - 87 EP - 90 JF - South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie JO - S Afr J Surg VL - 32 IS - 3 N2 - Distal splenorenal shunt (DSRS) is a once-only form of treatment. It is suitable for many black South Africans with non-cirrhotic variceal bleeding who cannot attend repeated follow-up sclerotherapy sessions. However, persistent hyperbilirubinaemia and encephalopathy may occur following DSRS in schistosomiasis. Forty-one consecutive patients with DSRS have been treated over a 7-year period. The causes of portal hypertension were schistosomiasis (32), portal vein thrombosis (8) and diffuse nodular hyperplasia (1). Operative mortality was 6%. Encephalopathy was observed in 1 patient. Galactose elimination capacity (GEC) and technetium-diethylenetriamine penta-acetic acid hepatic perfusion index (HPI) were used to assess liver function and hepatic perfusion pre- and postoperatively, respectively, in schistosomiasis. GEC was 348 +/- 37 (M +/- SD) before, compared with 343 +/- 67 postoperatively (P = 0.78). HPI showed long-term preservation of hepatopetal portal venous flow following DSRS. Morbidity and mortality were observed only in patients with schistosomiasis associated with hepatitis B chronic active hepatitis. DSRS is ideal treatment in selected patients with non-cirrhotic variceal bleeding. SN - 0038-2361 UR - https://www.unboundmedicine.com/medline/citation/7597501/Distal_splenorenal_shunt_for_non_cirrhotic_variceal_bleeding_in_black_South_Africans_ L2 - https://medlineplus.gov/gastrointestinalbleeding.html DB - PRIME DP - Unbound Medicine ER -