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[Porphyria in dermatology].
Nihon Rinsho. 1995 Jun; 53(6):1449-55.NR

Abstract

Porphyrins are fluorescent chemicals excited by visual light. Skin changes in patients with porphyrias develop when the skin is exposed to sunlight and porphyrins have precipitated. This reaction is phototoxic. Since the phototoxic reaction varies with each porphyria, each porphyria demonstrates different skin changes. Conversely, skin changes do not develop if skins are completely protected from exposure to the sun in patients with porphyrias with show severe abnormalities in the metabolism of porphyrin pathways. In Japan, relatively popular porphyrias in dermatology clinic are porphyria cutanea tarda (PCT), erythropoietic protoporphyria (EPP) and congenital erythropoietic porphyria (CEP). Histopathologically, one of the most important findings in porphyria is a deposition of PAS positive materials at the dermo-epidermal junction and around the small blood vessels in the dermis.

Authors+Show Affiliations

Department of Dermatology, Faculty of Medicine, University of the Ryukyus.No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

jpn

PubMed ID

7616662

Citation

Nonaka, S, et al. "[Porphyria in Dermatology]." Nihon Rinsho. Japanese Journal of Clinical Medicine, vol. 53, no. 6, 1995, pp. 1449-55.
Nonaka S, Takamiyagi A, Maruno M. [Porphyria in dermatology]. Nippon Rinsho. 1995;53(6):1449-55.
Nonaka, S., Takamiyagi, A., & Maruno, M. (1995). [Porphyria in dermatology]. Nihon Rinsho. Japanese Journal of Clinical Medicine, 53(6), 1449-55.
Nonaka S, Takamiyagi A, Maruno M. [Porphyria in Dermatology]. Nippon Rinsho. 1995;53(6):1449-55. PubMed PMID: 7616662.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Porphyria in dermatology]. AU - Nonaka,S, AU - Takamiyagi,A, AU - Maruno,M, PY - 1995/6/1/pubmed PY - 1995/6/1/medline PY - 1995/6/1/entrez SP - 1449 EP - 55 JF - Nihon rinsho. Japanese journal of clinical medicine JO - Nippon Rinsho VL - 53 IS - 6 N2 - Porphyrins are fluorescent chemicals excited by visual light. Skin changes in patients with porphyrias develop when the skin is exposed to sunlight and porphyrins have precipitated. This reaction is phototoxic. Since the phototoxic reaction varies with each porphyria, each porphyria demonstrates different skin changes. Conversely, skin changes do not develop if skins are completely protected from exposure to the sun in patients with porphyrias with show severe abnormalities in the metabolism of porphyrin pathways. In Japan, relatively popular porphyrias in dermatology clinic are porphyria cutanea tarda (PCT), erythropoietic protoporphyria (EPP) and congenital erythropoietic porphyria (CEP). Histopathologically, one of the most important findings in porphyria is a deposition of PAS positive materials at the dermo-epidermal junction and around the small blood vessels in the dermis. SN - 0047-1852 UR - https://www.unboundmedicine.com/medline/citation/7616662/[Porphyria_in_dermatology]_ L2 - http://www.diseaseinfosearch.org/result/5879 DB - PRIME DP - Unbound Medicine ER -
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