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Virucidal effects of the steam distillate from Houttuynia cordata and its components on HSV-1, influenza virus, and HIV.
Planta Med. 1995 Jun; 61(3):237-41.PM

Abstract

The steam distillate prepared from fresh plants of Houttuynia cordata Thunb. (Saururaceae) was found to have direct inhibitory activity against herpes simplex virus type 1 (HSV-1), influenza virus, and human immunodeficiency virus type 1 (HIV-1) without showing cytotoxicity, but not against poliovirus and coxsackie-virus. The loss of viral infectivity was related to the duration of drug treatment. Three major components of the distillate, methyl n-nonyl ketone, lauryl aldehyde, and capryl aldehyde, also inactivated HSV-1, influenza virus, and HIV-1. These in vitro findings demonstrate that the essential oils provide virucidal activity against enveloped viruses by interfering with the function of virus envelope.

Authors+Show Affiliations

Department of Virology, Toyama Medical and Pharmaceutical University, Japan.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

7617766

Citation

Hayashi, K, et al. "Virucidal Effects of the Steam Distillate From Houttuynia Cordata and Its Components On HSV-1, Influenza Virus, and HIV." Planta Medica, vol. 61, no. 3, 1995, pp. 237-41.
Hayashi K, Kamiya M, Hayashi T. Virucidal effects of the steam distillate from Houttuynia cordata and its components on HSV-1, influenza virus, and HIV. Planta Med. 1995;61(3):237-41.
Hayashi, K., Kamiya, M., & Hayashi, T. (1995). Virucidal effects of the steam distillate from Houttuynia cordata and its components on HSV-1, influenza virus, and HIV. Planta Medica, 61(3), 237-41.
Hayashi K, Kamiya M, Hayashi T. Virucidal Effects of the Steam Distillate From Houttuynia Cordata and Its Components On HSV-1, Influenza Virus, and HIV. Planta Med. 1995;61(3):237-41. PubMed PMID: 7617766.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Virucidal effects of the steam distillate from Houttuynia cordata and its components on HSV-1, influenza virus, and HIV. AU - Hayashi,K, AU - Kamiya,M, AU - Hayashi,T, PY - 1995/6/1/pubmed PY - 1995/6/1/medline PY - 1995/6/1/entrez SP - 237 EP - 41 JF - Planta medica JO - Planta Med VL - 61 IS - 3 N2 - The steam distillate prepared from fresh plants of Houttuynia cordata Thunb. (Saururaceae) was found to have direct inhibitory activity against herpes simplex virus type 1 (HSV-1), influenza virus, and human immunodeficiency virus type 1 (HIV-1) without showing cytotoxicity, but not against poliovirus and coxsackie-virus. The loss of viral infectivity was related to the duration of drug treatment. Three major components of the distillate, methyl n-nonyl ketone, lauryl aldehyde, and capryl aldehyde, also inactivated HSV-1, influenza virus, and HIV-1. These in vitro findings demonstrate that the essential oils provide virucidal activity against enveloped viruses by interfering with the function of virus envelope. SN - 0032-0943 UR - https://www.unboundmedicine.com/medline/citation/7617766/Virucidal_effects_of_the_steam_distillate_from_Houttuynia_cordata_and_its_components_on_HSV_1_influenza_virus_and_HIV_ DB - PRIME DP - Unbound Medicine ER -