Tags

Type your tag names separated by a space and hit enter

Mania-like symptoms suggestive of childhood-onset bipolar disorder in clinically referred children.
J Am Acad Child Adolesc Psychiatry. 1995 Jul; 34(7):867-76.JA

Abstract

OBJECTIVE

To examine the prevalence, characteristics, and correlates of mania among referred children aged 12 or younger. Many case reports challenge the widely accepted belief that childhood-onset mania is rare. Sources of diagnostic confusion include the variable developmental expression of mania and its symptomatic overlap with attention-deficit hyperactivity disorder (ADHD).

METHOD

The authors compared 43 children aged 12 years or younger who satisfied criteria for mania, 164 ADHD children without mania, and 84 non-ADHD control children.

RESULTS

The clinical picture was fully compatible with the DSM-III-R diagnosis of mania in 16% (n = 43) of referred children. All but one of the children meeting criteria for mania also met criteria for ADHD. Compared with ADHD children without mania, manic children had significantly higher rates of major depression, psychosis, multiple anxiety disorders, conduct disorder, and oppositional defiant disorder as well as evidence of significantly more impaired psychosocial functioning. In addition, 21% (n = 9) of manic children had had at least one previous psychiatric hospitalization.

CONCLUSIONS

Mania may be relatively common among psychiatrically referred children. The clinical picture of childhood-onset mania is very severe and frequently comorbid with ADHD and other psychiatric disorders. Because of the high comorbidity with ADHD, more work is needed to clarify whether these children have ADHD, bipolar disorder, or both.

Authors+Show Affiliations

Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston 02114, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

7649957

Citation

Wozniak, J, et al. "Mania-like Symptoms Suggestive of Childhood-onset Bipolar Disorder in Clinically Referred Children." Journal of the American Academy of Child and Adolescent Psychiatry, vol. 34, no. 7, 1995, pp. 867-76.
Wozniak J, Biederman J, Kiely K, et al. Mania-like symptoms suggestive of childhood-onset bipolar disorder in clinically referred children. J Am Acad Child Adolesc Psychiatry. 1995;34(7):867-76.
Wozniak, J., Biederman, J., Kiely, K., Ablon, J. S., Faraone, S. V., Mundy, E., & Mennin, D. (1995). Mania-like symptoms suggestive of childhood-onset bipolar disorder in clinically referred children. Journal of the American Academy of Child and Adolescent Psychiatry, 34(7), 867-76.
Wozniak J, et al. Mania-like Symptoms Suggestive of Childhood-onset Bipolar Disorder in Clinically Referred Children. J Am Acad Child Adolesc Psychiatry. 1995;34(7):867-76. PubMed PMID: 7649957.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mania-like symptoms suggestive of childhood-onset bipolar disorder in clinically referred children. AU - Wozniak,J, AU - Biederman,J, AU - Kiely,K, AU - Ablon,J S, AU - Faraone,S V, AU - Mundy,E, AU - Mennin,D, PY - 1995/7/1/pubmed PY - 1995/7/1/medline PY - 1995/7/1/entrez SP - 867 EP - 76 JF - Journal of the American Academy of Child and Adolescent Psychiatry JO - J Am Acad Child Adolesc Psychiatry VL - 34 IS - 7 N2 - OBJECTIVE: To examine the prevalence, characteristics, and correlates of mania among referred children aged 12 or younger. Many case reports challenge the widely accepted belief that childhood-onset mania is rare. Sources of diagnostic confusion include the variable developmental expression of mania and its symptomatic overlap with attention-deficit hyperactivity disorder (ADHD). METHOD: The authors compared 43 children aged 12 years or younger who satisfied criteria for mania, 164 ADHD children without mania, and 84 non-ADHD control children. RESULTS: The clinical picture was fully compatible with the DSM-III-R diagnosis of mania in 16% (n = 43) of referred children. All but one of the children meeting criteria for mania also met criteria for ADHD. Compared with ADHD children without mania, manic children had significantly higher rates of major depression, psychosis, multiple anxiety disorders, conduct disorder, and oppositional defiant disorder as well as evidence of significantly more impaired psychosocial functioning. In addition, 21% (n = 9) of manic children had had at least one previous psychiatric hospitalization. CONCLUSIONS: Mania may be relatively common among psychiatrically referred children. The clinical picture of childhood-onset mania is very severe and frequently comorbid with ADHD and other psychiatric disorders. Because of the high comorbidity with ADHD, more work is needed to clarify whether these children have ADHD, bipolar disorder, or both. SN - 0890-8567 UR - https://www.unboundmedicine.com/medline/citation/7649957/Mania_like_symptoms_suggestive_of_childhood_onset_bipolar_disorder_in_clinically_referred_children_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0890-8567(09)63597-8 DB - PRIME DP - Unbound Medicine ER -