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Shortening of life span and causes of excess mortality in a population-based series of subjects with rheumatoid arthritis.
Clin Exp Rheumatol. 1995 Mar-Apr; 13(2):149-53.CE

Abstract

OBJECTIVES

To obtain information on the shortening of the life span and the causes of excess death in a population-based series of subjects with rheumatoid arthritis (RA).

METHODS

The study included all 1666 subjects who had died in Finland in 1989 and were entitled under the nationwide sickness insurance scheme to receive specially reimbursed medication for RA. Demographic data on the Finnish population and sickness insurance statistics were used as the basis for computations.

RESULTS

The life span in subjects with RA was shortened by 15-20% from the date of onset of illness. The determinants of excess mortality could be studied in females. About 40% of the excess deaths were due to cardiovascular causes, 30% to infections, 15% to amyloidosis, and the remaining 15% to diverse causes.

CONCLUSION

This data provides an enlightened basis for understanding mortality associated with RA.

Authors+Show Affiliations

Rheumatism Foundation Hospital, Heinola, Finland.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

7656460

Citation

Myllykangas-Luosujärvi, R, et al. "Shortening of Life Span and Causes of Excess Mortality in a Population-based Series of Subjects With Rheumatoid Arthritis." Clinical and Experimental Rheumatology, vol. 13, no. 2, 1995, pp. 149-53.
Myllykangas-Luosujärvi R, Aho K, Kautiainen H, et al. Shortening of life span and causes of excess mortality in a population-based series of subjects with rheumatoid arthritis. Clin Exp Rheumatol. 1995;13(2):149-53.
Myllykangas-Luosujärvi, R., Aho, K., Kautiainen, H., & Isomäki, H. (1995). Shortening of life span and causes of excess mortality in a population-based series of subjects with rheumatoid arthritis. Clinical and Experimental Rheumatology, 13(2), 149-53.
Myllykangas-Luosujärvi R, et al. Shortening of Life Span and Causes of Excess Mortality in a Population-based Series of Subjects With Rheumatoid Arthritis. Clin Exp Rheumatol. 1995 Mar-Apr;13(2):149-53. PubMed PMID: 7656460.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Shortening of life span and causes of excess mortality in a population-based series of subjects with rheumatoid arthritis. AU - Myllykangas-Luosujärvi,R, AU - Aho,K, AU - Kautiainen,H, AU - Isomäki,H, PY - 1995/3/1/pubmed PY - 1995/3/1/medline PY - 1995/3/1/entrez SP - 149 EP - 53 JF - Clinical and experimental rheumatology JO - Clin Exp Rheumatol VL - 13 IS - 2 N2 - OBJECTIVES: To obtain information on the shortening of the life span and the causes of excess death in a population-based series of subjects with rheumatoid arthritis (RA). METHODS: The study included all 1666 subjects who had died in Finland in 1989 and were entitled under the nationwide sickness insurance scheme to receive specially reimbursed medication for RA. Demographic data on the Finnish population and sickness insurance statistics were used as the basis for computations. RESULTS: The life span in subjects with RA was shortened by 15-20% from the date of onset of illness. The determinants of excess mortality could be studied in females. About 40% of the excess deaths were due to cardiovascular causes, 30% to infections, 15% to amyloidosis, and the remaining 15% to diverse causes. CONCLUSION: This data provides an enlightened basis for understanding mortality associated with RA. SN - 0392-856X UR - https://www.unboundmedicine.com/medline/citation/7656460/Shortening_of_life_span_and_causes_of_excess_mortality_in_a_population_based_series_of_subjects_with_rheumatoid_arthritis_ L2 - http://www.diseaseinfosearch.org/result/592 DB - PRIME DP - Unbound Medicine ER -