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The efficacy of antivenom in the treatment of bites by the Papuan taipan (Oxyuranus scutellatus canni).
Trans R Soc Trop Med Hyg. 1995 May-Jun; 89(3):322-5.TR

Abstract

A prospective series of 156 patients systemically envenomed following the bite of a Papuan taipan (Oxyuranus scutellatus canni) were studied. All patients were treated with appropriate antivenom and clinical course and outcome were compared. The proportion of patients requiring intubation was significantly smaller, and the time to resolution of neurotoxicity and discharge from hospital significantly shorter, in patients receiving antivenom no more than 4 h after the bite. No significant difference in outcome was demonstrated between patients receiving antivenom at various times after 4 h. No difference was demonstrated in the times to restoration of coagulability between the 2 groups. The only significant difference between a small number of patients given 2 vials of antivenom and patients given a single vial at the same time after envenoming was a marginally shorter duration of intubation in those who required it. The study suggests that, to achieve significant clinical benefit in Papuan taipan bite, antivenom must be given as early as possible.

Authors+Show Affiliations

Department of Clinical Sciences, University of Papua New Guinea, Port Moresby.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

7660450

Citation

Trevett, A J., et al. "The Efficacy of Antivenom in the Treatment of Bites By the Papuan Taipan (Oxyuranus Scutellatus Canni)." Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 89, no. 3, 1995, pp. 322-5.
Trevett AJ, Lalloo DG, Nwokolo NC, et al. The efficacy of antivenom in the treatment of bites by the Papuan taipan (Oxyuranus scutellatus canni). Trans R Soc Trop Med Hyg. 1995;89(3):322-5.
Trevett, A. J., Lalloo, D. G., Nwokolo, N. C., Naraqi, S., Kevau, I. H., Theakston, R. D., & Warrell, D. A. (1995). The efficacy of antivenom in the treatment of bites by the Papuan taipan (Oxyuranus scutellatus canni). Transactions of the Royal Society of Tropical Medicine and Hygiene, 89(3), 322-5.
Trevett AJ, et al. The Efficacy of Antivenom in the Treatment of Bites By the Papuan Taipan (Oxyuranus Scutellatus Canni). Trans R Soc Trop Med Hyg. 1995 May-Jun;89(3):322-5. PubMed PMID: 7660450.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The efficacy of antivenom in the treatment of bites by the Papuan taipan (Oxyuranus scutellatus canni). AU - Trevett,A J, AU - Lalloo,D G, AU - Nwokolo,N C, AU - Naraqi,S, AU - Kevau,I H, AU - Theakston,R D, AU - Warrell,D A, PY - 1995/5/1/pubmed PY - 1995/5/1/medline PY - 1995/5/1/entrez SP - 322 EP - 5 JF - Transactions of the Royal Society of Tropical Medicine and Hygiene JO - Trans. R. Soc. Trop. Med. Hyg. VL - 89 IS - 3 N2 - A prospective series of 156 patients systemically envenomed following the bite of a Papuan taipan (Oxyuranus scutellatus canni) were studied. All patients were treated with appropriate antivenom and clinical course and outcome were compared. The proportion of patients requiring intubation was significantly smaller, and the time to resolution of neurotoxicity and discharge from hospital significantly shorter, in patients receiving antivenom no more than 4 h after the bite. No significant difference in outcome was demonstrated between patients receiving antivenom at various times after 4 h. No difference was demonstrated in the times to restoration of coagulability between the 2 groups. The only significant difference between a small number of patients given 2 vials of antivenom and patients given a single vial at the same time after envenoming was a marginally shorter duration of intubation in those who required it. The study suggests that, to achieve significant clinical benefit in Papuan taipan bite, antivenom must be given as early as possible. SN - 0035-9203 UR - https://www.unboundmedicine.com/medline/citation/7660450/The_efficacy_of_antivenom_in_the_treatment_of_bites_by_the_Papuan_taipan__Oxyuranus_scutellatus_canni__ L2 - https://academic.oup.com/trstmh/article-lookup/doi/10.1016/0035-9203(95)90562-6 DB - PRIME DP - Unbound Medicine ER -