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Biochemical folate, B12, and iron status of a group of pregnant adolescents accessed through the public health system in southern Ontario.
J Adolesc Health. 1995 Jun; 16(6):465-74.JA

Abstract

PURPOSE

This study was designed to estimate the prevalence of biochemical iron, folate, and vitamin B12 depletion among a group of Canadian pregnant adolescents accessed through the Public Health system. Further, the impact of prenatal supplement use, chronologic age, gynecologic age, living arrangement, main source of income, postpartum custody plan, time of entry into prenatal care, and cigarette smoking on laboratory indices of the three nutrients were determined.

METHODS

Fifty-eight adolescents (14.5-19.0 years) were interviewed and blood samples were collected at 36 +/- 2 wk gestation.

RESULTS

Thirteen (22%) of the pregnant adolescents had anemia (hemoglobin < 110 g/L) and forty-five (78%) had depleted iron stores (plasma ferritin < 26.6 pmol/L or 12.0 micrograms/L). Twenty-five subjects had plasma B12 values in the sub-optimal range (< 148 pmol/L). Five of the 16 adolescents who infrequently or never consumed a folate-containing supplement had suboptimal erythrocyte folate values. Twenty-four percent of the subjects had hypersegmented neutrophils and of these, all and 71% of subjects had plasma ferritin and B12 concentrations in the suboptimal range, respectively. Self-reported folic acid and B12 supplement intakes were correlated with the corresponding blood values for these nutrients. In contrast, supplement iron use was only weakly, or not at all associated with biochemical indices of iron status.

CONCLUSIONS

Data from the present study indicate that plasma B12 and ferritin levels are low in a group of pregnant adolescents. These low values appear to be associated with a high prevalence of hypersegmented neutrophils. Prenatal supplement use appears to reduce the risk of low folate and B12 blood values but not biochemical iron status.

Authors+Show Affiliations

Division of Applied Human Nutrition, University of Guelph, Ontario, Canada.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

7669797

Citation

Gadowsky, S L., et al. "Biochemical Folate, B12, and Iron Status of a Group of Pregnant Adolescents Accessed Through the Public Health System in Southern Ontario." The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine, vol. 16, no. 6, 1995, pp. 465-74.
Gadowsky SL, Gale K, Wolfe SA, et al. Biochemical folate, B12, and iron status of a group of pregnant adolescents accessed through the public health system in southern Ontario. J Adolesc Health. 1995;16(6):465-74.
Gadowsky, S. L., Gale, K., Wolfe, S. A., Jory, J., Gibson, R., & O'Connor, D. L. (1995). Biochemical folate, B12, and iron status of a group of pregnant adolescents accessed through the public health system in southern Ontario. The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine, 16(6), 465-74.
Gadowsky SL, et al. Biochemical Folate, B12, and Iron Status of a Group of Pregnant Adolescents Accessed Through the Public Health System in Southern Ontario. J Adolesc Health. 1995;16(6):465-74. PubMed PMID: 7669797.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Biochemical folate, B12, and iron status of a group of pregnant adolescents accessed through the public health system in southern Ontario. AU - Gadowsky,S L, AU - Gale,K, AU - Wolfe,S A, AU - Jory,J, AU - Gibson,R, AU - O'Connor,D L, PY - 1995/6/1/pubmed PY - 1995/6/1/medline PY - 1995/6/1/entrez SP - 465 EP - 74 JF - The Journal of adolescent health : official publication of the Society for Adolescent Medicine JO - J Adolesc Health VL - 16 IS - 6 N2 - PURPOSE: This study was designed to estimate the prevalence of biochemical iron, folate, and vitamin B12 depletion among a group of Canadian pregnant adolescents accessed through the Public Health system. Further, the impact of prenatal supplement use, chronologic age, gynecologic age, living arrangement, main source of income, postpartum custody plan, time of entry into prenatal care, and cigarette smoking on laboratory indices of the three nutrients were determined. METHODS: Fifty-eight adolescents (14.5-19.0 years) were interviewed and blood samples were collected at 36 +/- 2 wk gestation. RESULTS: Thirteen (22%) of the pregnant adolescents had anemia (hemoglobin < 110 g/L) and forty-five (78%) had depleted iron stores (plasma ferritin < 26.6 pmol/L or 12.0 micrograms/L). Twenty-five subjects had plasma B12 values in the sub-optimal range (< 148 pmol/L). Five of the 16 adolescents who infrequently or never consumed a folate-containing supplement had suboptimal erythrocyte folate values. Twenty-four percent of the subjects had hypersegmented neutrophils and of these, all and 71% of subjects had plasma ferritin and B12 concentrations in the suboptimal range, respectively. Self-reported folic acid and B12 supplement intakes were correlated with the corresponding blood values for these nutrients. In contrast, supplement iron use was only weakly, or not at all associated with biochemical indices of iron status. CONCLUSIONS: Data from the present study indicate that plasma B12 and ferritin levels are low in a group of pregnant adolescents. These low values appear to be associated with a high prevalence of hypersegmented neutrophils. Prenatal supplement use appears to reduce the risk of low folate and B12 blood values but not biochemical iron status. SN - 1054-139X UR - https://www.unboundmedicine.com/medline/citation/7669797/Biochemical_folate_B12_and_iron_status_of_a_group_of_pregnant_adolescents_accessed_through_the_public_health_system_in_southern_Ontario_ L2 - https://linkinghub.elsevier.com/retrieve/pii/1054-139X(94)00001-U DB - PRIME DP - Unbound Medicine ER -