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Parkinson's disease: managing symptoms and preserving function.
Geriatrics. 1995 Sep; 50(9):24-31.G

Abstract

Two strategies of drug therapy for Parkinson's disease (PD) are neuroprotective and symptomatic. In early PD, selegiline may delay need for symptomatic treatment, but whether this represents a delay in disease progression remains controversial. The decision to begin symptomatic therapy depends on how disabling or troublesome symptoms are to the patient. Anticholinergics are often used as monotherapy for alleviation of early tremor. When levodopa is added, it may be reasonable to begin with the controlled-release form. The variety of dopamine agonists used as adjunctive agents is increasing. Research continues on surgical therapies and fetal tissue transplantation.

Authors+Show Affiliations

Department of Neurology, Cleveland Clinic Foundation, OH, USA.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

7672615

Citation

Sweeney, P J.. "Parkinson's Disease: Managing Symptoms and Preserving Function." Geriatrics, vol. 50, no. 9, 1995, pp. 24-31.
Sweeney PJ. Parkinson's disease: managing symptoms and preserving function. Geriatrics. 1995;50(9):24-31.
Sweeney, P. J. (1995). Parkinson's disease: managing symptoms and preserving function. Geriatrics, 50(9), 24-31.
Sweeney PJ. Parkinson's Disease: Managing Symptoms and Preserving Function. Geriatrics. 1995;50(9):24-31. PubMed PMID: 7672615.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Parkinson's disease: managing symptoms and preserving function. A1 - Sweeney,P J, PY - 1995/9/1/pubmed PY - 1995/9/1/medline PY - 1995/9/1/entrez SP - 24 EP - 31 JF - Geriatrics JO - Geriatrics VL - 50 IS - 9 N2 - Two strategies of drug therapy for Parkinson's disease (PD) are neuroprotective and symptomatic. In early PD, selegiline may delay need for symptomatic treatment, but whether this represents a delay in disease progression remains controversial. The decision to begin symptomatic therapy depends on how disabling or troublesome symptoms are to the patient. Anticholinergics are often used as monotherapy for alleviation of early tremor. When levodopa is added, it may be reasonable to begin with the controlled-release form. The variety of dopamine agonists used as adjunctive agents is increasing. Research continues on surgical therapies and fetal tissue transplantation. SN - 0016-867X UR - https://www.unboundmedicine.com/medline/citation/7672615/Parkinson's_disease:_managing_symptoms_and_preserving_function_ L2 - https://medlineplus.gov/parkinsonsdisease.html DB - PRIME DP - Unbound Medicine ER -