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[Sideropenic anemia and celiac disease].
Pediatr Med Chir 1994 Nov-Dec; 16(6):549-50PM

Abstract

Since the beginning of the use of Antigliadin Antibodies (AGA) in the screening of coeliac disease (CD) we have observed an increasing in the total number of cases diagnosed, in particular of the cases with monosymptomatic and atypical forms. Iron deficiency anemia is one of the more frequent findings that we can find in CD, either in association with other typical coeliac signs, or as an isolated expression of the disease. The first aim of our study was to determine the incidence of iron deficiency anemia in our patients affected by CD at the moment of diagnosis. The second aim was to determine the incidence of CD in a group of 96 patients attending our Pediatric Hematology department for iron deficiency anemia of unknown etiology and refractory to iron therapy. 103 patients out of our 212 coeliacs (48.5%) showed hypochromic and microcytic anemia. In the second sample we found 6 (6.2%) patients, positive in AGA and Antiendomysium Antibodies (AEA), that showed a typical coeliac picture at the jejunal biopsy. Our study confirms the high incidence of iron deficiency anemia in patients affected by coeliac disease. However the most important conclusion of our study is that a certain percentage of patients affected by hypochromic anemia of unknown etiology may be affected by coeliac disease. It is only by performing the specific screening tests (AGA and AEA) in the patients affected by iron deficiency anemia of unknown etiology, that we can diagnose this monosymptomatic expression of CD.

Authors+Show Affiliations

Clinica Pediatrica III, Università di Bologna, Italia.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

ita

PubMed ID

7708537

Citation

Lazzari, R, et al. "[Sideropenic Anemia and Celiac Disease]." La Pediatria Medica E Chirurgica : Medical and Surgical Pediatrics, vol. 16, no. 6, 1994, pp. 549-50.
Lazzari R, Collina A, Arena G, et al. [Sideropenic anemia and celiac disease]. Pediatr Med Chir. 1994;16(6):549-50.
Lazzari, R., Collina, A., Arena, G., Bochicchio, A., Corvaglia, L., Vallini, M., ... Frassineti, S. (1994). [Sideropenic anemia and celiac disease]. La Pediatria Medica E Chirurgica : Medical and Surgical Pediatrics, 16(6), pp. 549-50.
Lazzari R, et al. [Sideropenic Anemia and Celiac Disease]. Pediatr Med Chir. 1994;16(6):549-50. PubMed PMID: 7708537.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Sideropenic anemia and celiac disease]. AU - Lazzari,R, AU - Collina,A, AU - Arena,G, AU - Bochicchio,A, AU - Corvaglia,L, AU - Vallini,M, AU - Marzatico,M, AU - Forchielli,L, AU - Pasetti,A, AU - Frassineti,S, PY - 1994/11/1/pubmed PY - 1994/11/1/medline PY - 1994/11/1/entrez SP - 549 EP - 50 JF - La Pediatria medica e chirurgica : Medical and surgical pediatrics JO - Pediatr Med Chir VL - 16 IS - 6 N2 - Since the beginning of the use of Antigliadin Antibodies (AGA) in the screening of coeliac disease (CD) we have observed an increasing in the total number of cases diagnosed, in particular of the cases with monosymptomatic and atypical forms. Iron deficiency anemia is one of the more frequent findings that we can find in CD, either in association with other typical coeliac signs, or as an isolated expression of the disease. The first aim of our study was to determine the incidence of iron deficiency anemia in our patients affected by CD at the moment of diagnosis. The second aim was to determine the incidence of CD in a group of 96 patients attending our Pediatric Hematology department for iron deficiency anemia of unknown etiology and refractory to iron therapy. 103 patients out of our 212 coeliacs (48.5%) showed hypochromic and microcytic anemia. In the second sample we found 6 (6.2%) patients, positive in AGA and Antiendomysium Antibodies (AEA), that showed a typical coeliac picture at the jejunal biopsy. Our study confirms the high incidence of iron deficiency anemia in patients affected by coeliac disease. However the most important conclusion of our study is that a certain percentage of patients affected by hypochromic anemia of unknown etiology may be affected by coeliac disease. It is only by performing the specific screening tests (AGA and AEA) in the patients affected by iron deficiency anemia of unknown etiology, that we can diagnose this monosymptomatic expression of CD. SN - 0391-5387 UR - https://www.unboundmedicine.com/medline/citation/7708537/[Sideropenic_anemia_and_celiac_disease]_ L2 - http://www.diseaseinfosearch.org/result/1186 DB - PRIME DP - Unbound Medicine ER -