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No association between serum ferritin and asymptomatic carotid atherosclerosis. The Atherosclerosis Risk in Communities (ARIC) Study.
Am J Epidemiol 1995; 141(8):719-23AJ

Abstract

A possible association between body iron stores, measured as serum ferritin, and carotid arterial intima-media thickening was investigated in the Atherosclerosis Risk in Communities Study during 1990-1992 using a matched case-control design. For a 143-micrograms/liter greater serum ferritin concentration (the interquartile range), the odds ratio for cases with carotid intima-media thickening versus controls was 1.12 (95% confidence interval 0.97-1.30). However, there was no association (odds ratio = 1.00) after adjusting for major cardiovascular risk factors. This analysis of carotid arterial intima-media thickening, a measure of early atherosclerosis, in relation to serum ferritin does not support the hypothesis that increased body iron stores increase the risk of atherosclerotic cardiovascular disease.

Authors+Show Affiliations

Mayo Graduate School of Medicine, Rochester, MN, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

7709914

Citation

Moore, M, et al. "No Association Between Serum Ferritin and Asymptomatic Carotid Atherosclerosis. the Atherosclerosis Risk in Communities (ARIC) Study." American Journal of Epidemiology, vol. 141, no. 8, 1995, pp. 719-23.
Moore M, Folsom AR, Barnes RW, et al. No association between serum ferritin and asymptomatic carotid atherosclerosis. The Atherosclerosis Risk in Communities (ARIC) Study. Am J Epidemiol. 1995;141(8):719-23.
Moore, M., Folsom, A. R., Barnes, R. W., & Eckfeldt, J. H. (1995). No association between serum ferritin and asymptomatic carotid atherosclerosis. The Atherosclerosis Risk in Communities (ARIC) Study. American Journal of Epidemiology, 141(8), pp. 719-23.
Moore M, et al. No Association Between Serum Ferritin and Asymptomatic Carotid Atherosclerosis. the Atherosclerosis Risk in Communities (ARIC) Study. Am J Epidemiol. 1995 Apr 15;141(8):719-23. PubMed PMID: 7709914.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - No association between serum ferritin and asymptomatic carotid atherosclerosis. The Atherosclerosis Risk in Communities (ARIC) Study. AU - Moore,M, AU - Folsom,A R, AU - Barnes,R W, AU - Eckfeldt,J H, PY - 1995/4/15/pubmed PY - 1995/4/15/medline PY - 1995/4/15/entrez SP - 719 EP - 23 JF - American journal of epidemiology JO - Am. J. Epidemiol. VL - 141 IS - 8 N2 - A possible association between body iron stores, measured as serum ferritin, and carotid arterial intima-media thickening was investigated in the Atherosclerosis Risk in Communities Study during 1990-1992 using a matched case-control design. For a 143-micrograms/liter greater serum ferritin concentration (the interquartile range), the odds ratio for cases with carotid intima-media thickening versus controls was 1.12 (95% confidence interval 0.97-1.30). However, there was no association (odds ratio = 1.00) after adjusting for major cardiovascular risk factors. This analysis of carotid arterial intima-media thickening, a measure of early atherosclerosis, in relation to serum ferritin does not support the hypothesis that increased body iron stores increase the risk of atherosclerotic cardiovascular disease. SN - 0002-9262 UR - https://www.unboundmedicine.com/medline/citation/7709914/No_association_between_serum_ferritin_and_asymptomatic_carotid_atherosclerosis__The_Atherosclerosis_Risk_in_Communities__ARIC__Study_ L2 - https://academic.oup.com/aje/article-lookup/doi/10.1093/oxfordjournals.aje.a117493 DB - PRIME DP - Unbound Medicine ER -