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Atypical ductal hyperplasia diagnosed at stereotaxic core biopsy of breast lesions: an indication for surgical biopsy.
AJR Am J Roentgenol. 1995 May; 164(5):1111-3.AA

Abstract

OBJECTIVE

The purpose of this study was to evaluate the prevalence of carcinoma found at surgical biopsy of lesions identified as atypical ductal hyperplasia by stereotaxic core breast biopsy.

SUBJECTS AND METHODS

Stereotaxic core biopsies of 264 mammographically evident lesions were done with the patients lying prone on a dedicated stereotaxic table, with an automated gun and a 14-gauge needle. Atypical ductal hyperplasia was identified in 25 (9%) of 264 lesions, including four (3%) of 159 masses and 21 (20%) of 105 lesions evident as calcifications. Surgical biopsy was recommended in all 25 of these cases and was performed in 21. Results of stereotaxic core biopsy and surgery in these 21 cases were reviewed and correlated.

RESULTS

Of 21 cases identified as atypical ductal hyperplasia at stereotaxic core biopsy that were subsequently evaluated with surgical biopsy, histopathologic analysis of the surgical specimen yielded benign histologic findings without atypia in four (19%), atypical ductal hyperplasia in six (29%), and carcinoma in 11 (52%). Of the 11 carcinomas, histologic findings showed ductal carcinoma in situ in eight (73%) and invasive ductal carcinoma in three (27%).

CONCLUSION

The finding of atypical ductal hyperplasia at stereotaxic core breast biopsy is an indication for surgical biopsy because of the high prevalence of ductal carcinoma in these lesions.

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Authors+Show Affiliations

Liberman L
Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
Cohen MA
No affiliation info available
Dershaw DD
No affiliation info available
Abramson AF
No affiliation info available
Hann LE
No affiliation info available
Rosen PP
No affiliation info available

MeSH

Biopsy, NeedleBreastBreast NeoplasmsCarcinoma in SituCarcinoma, Ductal, BreastFemaleHumansHyperplasiaMammographyMiddle AgedPrevalenceStereotaxic Techniques

Pub Type(s)

Journal Article

Language

eng

PubMed ID

7717215

Citation

Liberman, L, et al. "Atypical Ductal Hyperplasia Diagnosed at Stereotaxic Core Biopsy of Breast Lesions: an Indication for Surgical Biopsy." AJR. American Journal of Roentgenology, vol. 164, no. 5, 1995, pp. 1111-3.
Liberman L, Cohen MA, Dershaw DD, et al. Atypical ductal hyperplasia diagnosed at stereotaxic core biopsy of breast lesions: an indication for surgical biopsy. AJR Am J Roentgenol. 1995;164(5):1111-3.
Liberman, L., Cohen, M. A., Dershaw, D. D., Abramson, A. F., Hann, L. E., & Rosen, P. P. (1995). Atypical ductal hyperplasia diagnosed at stereotaxic core biopsy of breast lesions: an indication for surgical biopsy. AJR. American Journal of Roentgenology, 164(5), 1111-3.
Liberman L, et al. Atypical Ductal Hyperplasia Diagnosed at Stereotaxic Core Biopsy of Breast Lesions: an Indication for Surgical Biopsy. AJR Am J Roentgenol. 1995;164(5):1111-3. PubMed PMID: 7717215.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Atypical ductal hyperplasia diagnosed at stereotaxic core biopsy of breast lesions: an indication for surgical biopsy. AU - Liberman,L, AU - Cohen,M A, AU - Dershaw,D D, AU - Abramson,A F, AU - Hann,L E, AU - Rosen,P P, PY - 1995/5/1/pubmed PY - 1995/5/1/medline PY - 1995/5/1/entrez SP - 1111 EP - 3 JF - AJR. American journal of roentgenology JO - AJR Am J Roentgenol VL - 164 IS - 5 N2 - OBJECTIVE: The purpose of this study was to evaluate the prevalence of carcinoma found at surgical biopsy of lesions identified as atypical ductal hyperplasia by stereotaxic core breast biopsy. SUBJECTS AND METHODS: Stereotaxic core biopsies of 264 mammographically evident lesions were done with the patients lying prone on a dedicated stereotaxic table, with an automated gun and a 14-gauge needle. Atypical ductal hyperplasia was identified in 25 (9%) of 264 lesions, including four (3%) of 159 masses and 21 (20%) of 105 lesions evident as calcifications. Surgical biopsy was recommended in all 25 of these cases and was performed in 21. Results of stereotaxic core biopsy and surgery in these 21 cases were reviewed and correlated. RESULTS: Of 21 cases identified as atypical ductal hyperplasia at stereotaxic core biopsy that were subsequently evaluated with surgical biopsy, histopathologic analysis of the surgical specimen yielded benign histologic findings without atypia in four (19%), atypical ductal hyperplasia in six (29%), and carcinoma in 11 (52%). Of the 11 carcinomas, histologic findings showed ductal carcinoma in situ in eight (73%) and invasive ductal carcinoma in three (27%). CONCLUSION: The finding of atypical ductal hyperplasia at stereotaxic core breast biopsy is an indication for surgical biopsy because of the high prevalence of ductal carcinoma in these lesions. SN - 0361-803X UR - https://www.unboundmedicine.com/medline/citation/7717215/Atypical_ductal_hyperplasia_diagnosed_at_stereotaxic_core_biopsy_of_breast_lesions:_an_indication_for_surgical_biopsy_ L2 - https://www.ajronline.org/doi/10.2214/ajr.164.5.7717215 DB - PRIME DP - Unbound Medicine ER -