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Sense and nonsense of influenza vaccination in asthma and chronic obstructive pulmonary disease.
Am J Respir Crit Care Med 1995; 151(5):1682-5; discussion 1685-6AJ

Abstract

Although influenza is generally seen as an important cause of excess mortality in patients with asthma or chronic obstructive pulmonary disease (COPD), this mortality is nearly exclusively present in patients over the age of 60. Morbidity in patients with asthma or COPD is related to respiratory infections, including influenza. Vaccination against influenza has proven to be effective in nursing home populations, decreasing both mortality and morbidity during epidemics of influenza A. In younger patients with asthma or COPD, however, the effect of vaccination is more ambiguous. Exacerbation of respiratory disease is not due to influenza vaccination (except in allergy to chicken protein), from which we can conclude that influenza vaccination is a safe method to prevent a potentially serious respiratory infection in patients with asthma or COPD.

Authors+Show Affiliations

University Hospital Rotterdam, Department of Virology, The Netherlands.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

7735634

Citation

Rothbarth, P H., et al. "Sense and Nonsense of Influenza Vaccination in Asthma and Chronic Obstructive Pulmonary Disease." American Journal of Respiratory and Critical Care Medicine, vol. 151, no. 5, 1995, pp. 1682-5; discussion 1685-6.
Rothbarth PH, Kempen BM, Sprenger MJ. Sense and nonsense of influenza vaccination in asthma and chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 1995;151(5):1682-5; discussion 1685-6.
Rothbarth, P. H., Kempen, B. M., & Sprenger, M. J. (1995). Sense and nonsense of influenza vaccination in asthma and chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine, 151(5), pp. 1682-5; discussion 1685-6.
Rothbarth PH, Kempen BM, Sprenger MJ. Sense and Nonsense of Influenza Vaccination in Asthma and Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 1995;151(5):1682-5; discussion 1685-6. PubMed PMID: 7735634.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sense and nonsense of influenza vaccination in asthma and chronic obstructive pulmonary disease. AU - Rothbarth,P H, AU - Kempen,B M, AU - Sprenger,M J, PY - 1995/5/1/pubmed PY - 1995/5/1/medline PY - 1995/5/1/entrez SP - 1682-5; discussion 1685-6 JF - American journal of respiratory and critical care medicine JO - Am. J. Respir. Crit. Care Med. VL - 151 IS - 5 N2 - Although influenza is generally seen as an important cause of excess mortality in patients with asthma or chronic obstructive pulmonary disease (COPD), this mortality is nearly exclusively present in patients over the age of 60. Morbidity in patients with asthma or COPD is related to respiratory infections, including influenza. Vaccination against influenza has proven to be effective in nursing home populations, decreasing both mortality and morbidity during epidemics of influenza A. In younger patients with asthma or COPD, however, the effect of vaccination is more ambiguous. Exacerbation of respiratory disease is not due to influenza vaccination (except in allergy to chicken protein), from which we can conclude that influenza vaccination is a safe method to prevent a potentially serious respiratory infection in patients with asthma or COPD. SN - 1073-449X UR - https://www.unboundmedicine.com/medline/citation/7735634/Sense_and_nonsense_of_influenza_vaccination_in_asthma_and_chronic_obstructive_pulmonary_disease_ L2 - http://www.atsjournals.org/doi/full/10.1164/ajrccm/151.5_Pt_1.1682?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -