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Lues maligna, or ulceronodular syphilis, in a man infected with human immunodeficiency virus: case report and review.
Clin Infect Dis. 1995 Feb; 20(2):387-90.CI

Abstract

A 30-year-old bisexual man who was infected with human immunodeficiency virus (HIV) and had a history of anaphylaxis to penicillin developed lues maligna, or ulceronodular secondary syphilis. Therapy with parenteral erythromycin failed, and he was subsequently treated with ceftriaxone following penicillin desensitization. A review of the English-language literature identified 14 cases of lues maligna reported between the early 1900s and 1988. From 1989 to 1994, an additional 12 cases (including the current case) were reported. Of those 12 cases, 11 occurred in patients who either were infected with HIV or were at high risk for HIV infection. Patients infected with HIV may be at increased risk of developing this severe form of secondary syphilis. Lues maligna should be considered in the differential diagnosis of HIV-infected patients who present with ulceronodular lesions.

Authors+Show Affiliations

Division of Infectious Diseases (Department of Medicine), Baystate Medical Center, Springfield, Massachusetts 01199, USA.No affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

7742445

Citation

Sands, M, and A Markus. "Lues Maligna, or Ulceronodular Syphilis, in a Man Infected With Human Immunodeficiency Virus: Case Report and Review." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, vol. 20, no. 2, 1995, pp. 387-90.
Sands M, Markus A. Lues maligna, or ulceronodular syphilis, in a man infected with human immunodeficiency virus: case report and review. Clin Infect Dis. 1995;20(2):387-90.
Sands, M., & Markus, A. (1995). Lues maligna, or ulceronodular syphilis, in a man infected with human immunodeficiency virus: case report and review. Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, 20(2), 387-90.
Sands M, Markus A. Lues Maligna, or Ulceronodular Syphilis, in a Man Infected With Human Immunodeficiency Virus: Case Report and Review. Clin Infect Dis. 1995;20(2):387-90. PubMed PMID: 7742445.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Lues maligna, or ulceronodular syphilis, in a man infected with human immunodeficiency virus: case report and review. AU - Sands,M, AU - Markus,A, PY - 1995/2/1/pubmed PY - 1995/2/1/medline PY - 1995/2/1/entrez SP - 387 EP - 90 JF - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America JO - Clin. Infect. Dis. VL - 20 IS - 2 N2 - A 30-year-old bisexual man who was infected with human immunodeficiency virus (HIV) and had a history of anaphylaxis to penicillin developed lues maligna, or ulceronodular secondary syphilis. Therapy with parenteral erythromycin failed, and he was subsequently treated with ceftriaxone following penicillin desensitization. A review of the English-language literature identified 14 cases of lues maligna reported between the early 1900s and 1988. From 1989 to 1994, an additional 12 cases (including the current case) were reported. Of those 12 cases, 11 occurred in patients who either were infected with HIV or were at high risk for HIV infection. Patients infected with HIV may be at increased risk of developing this severe form of secondary syphilis. Lues maligna should be considered in the differential diagnosis of HIV-infected patients who present with ulceronodular lesions. SN - 1058-4838 UR - https://www.unboundmedicine.com/medline/citation/7742445/Lues_maligna_or_ulceronodular_syphilis_in_a_man_infected_with_human_immunodeficiency_virus:_case_report_and_review_ L2 - https://academic.oup.com/cid/article-lookup/doi/10.1093/clinids/20.2.387 DB - PRIME DP - Unbound Medicine ER -