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Endoscopic sclerotherapy versus oesophageal transection in the prevention of variceal rebleeding.
Eur J Gastroenterol Hepatol. 1995 Mar; 7(3):231-5.EJ

Abstract

OBJECTIVE

To compare sclerotherapy with oesophageal transection in the prevention of rebleeding in patients with oesophageal varices.

DESIGN

A prospective trial.

PATIENTS

Forty-one patients with cirrhosis and variceal bleeding.

METHODS

After recovering from an acute episode of oesophageal variceal bleeding patients were randomized into two groups. One patient was excluded. Twenty-two patients were treated with sclerotherapy (group 1) and 18 underwent an oesophageal transection (group 2), with a shorter elapsed time from randomization to treatment in group 1. Both groups were similar with regard to clinical and biochemical features and variceal size. Failure, defined in group 1 as rebleeding or incomplete eradication after four sclerotherapy sessions, occurred in five (22.7%) patients; in group 2, rebleeding occurred in two (11.1%) patients (no statistically significant difference).

CONCLUSION

Although the survival rate was similar in both groups, sclerotherapy is preferable to oesophageal transection because it requires a shorter duration of hospitalization and has fewer complications.

Authors+Show Affiliations

Department of Gastroenterology, University Hospital La FE, Valencia, Spain.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

7743305

Citation

Nos, P, et al. "Endoscopic Sclerotherapy Versus Oesophageal Transection in the Prevention of Variceal Rebleeding." European Journal of Gastroenterology & Hepatology, vol. 7, no. 3, 1995, pp. 231-5.
Nos P, Sala T, Pertejo V, et al. Endoscopic sclerotherapy versus oesophageal transection in the prevention of variceal rebleeding. Eur J Gastroenterol Hepatol. 1995;7(3):231-5.
Nos, P., Sala, T., Pertejo, V., Berenguer, M., Garrigues, V., Pons, V., Juan, M., & Berenguer, J. (1995). Endoscopic sclerotherapy versus oesophageal transection in the prevention of variceal rebleeding. European Journal of Gastroenterology & Hepatology, 7(3), 231-5.
Nos P, et al. Endoscopic Sclerotherapy Versus Oesophageal Transection in the Prevention of Variceal Rebleeding. Eur J Gastroenterol Hepatol. 1995;7(3):231-5. PubMed PMID: 7743305.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Endoscopic sclerotherapy versus oesophageal transection in the prevention of variceal rebleeding. AU - Nos,P, AU - Sala,T, AU - Pertejo,V, AU - Berenguer,M, AU - Garrigues,V, AU - Pons,V, AU - Juan,M, AU - Berenguer,J, PY - 1995/3/1/pubmed PY - 1995/3/1/medline PY - 1995/3/1/entrez SP - 231 EP - 5 JF - European journal of gastroenterology & hepatology JO - Eur J Gastroenterol Hepatol VL - 7 IS - 3 N2 - OBJECTIVE: To compare sclerotherapy with oesophageal transection in the prevention of rebleeding in patients with oesophageal varices. DESIGN: A prospective trial. PATIENTS: Forty-one patients with cirrhosis and variceal bleeding. METHODS: After recovering from an acute episode of oesophageal variceal bleeding patients were randomized into two groups. One patient was excluded. Twenty-two patients were treated with sclerotherapy (group 1) and 18 underwent an oesophageal transection (group 2), with a shorter elapsed time from randomization to treatment in group 1. Both groups were similar with regard to clinical and biochemical features and variceal size. Failure, defined in group 1 as rebleeding or incomplete eradication after four sclerotherapy sessions, occurred in five (22.7%) patients; in group 2, rebleeding occurred in two (11.1%) patients (no statistically significant difference). CONCLUSION: Although the survival rate was similar in both groups, sclerotherapy is preferable to oesophageal transection because it requires a shorter duration of hospitalization and has fewer complications. SN - 0954-691X UR - https://www.unboundmedicine.com/medline/citation/7743305/Endoscopic_sclerotherapy_versus_oesophageal_transection_in_the_prevention_of_variceal_rebleeding_ L2 - https://medlineplus.gov/endoscopy.html DB - PRIME DP - Unbound Medicine ER -