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[Application of fragrances to treatments for depression].

Abstract

High pressure stress was found to induce immunosuppression accompanied with the enhancement of motor activity in mice. Citrus fragrance restored stress-induced immunosuppression and induced calm behavior in mice. In the forced swimming test using rats, citrus fragrance reduced the total immobility time and potentiated the imipramine-induced reduction in total immobility time. The application of citrus fragrance to depressive patients made it possible to markedly reduce the doses of antidepressants needed for the treatment of patients.

Authors

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Source

MeSH

Adult
Animals
Citrus
Depression
Humans
Male
Mice
Mice, Inbred BALB C
Middle Aged
Neuroimmunomodulation
Odors
Rats
Rats, Sprague-Dawley

Pub Type(s)

Clinical Trial
English Abstract
Journal Article

Language

jpn

PubMed ID

7750015