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Spontaneous spinal epidural hematoma in a patient with a mechanical aortic valve taking warfarin.
Can J Cardiol. 1995 May; 11(5):429-32.CJ

Abstract

A 59-year-old male with a mechanical aortic valve taking warfarin presented to hospital with Brown-Séquard syndrome caused by a spontaneous spinal epidural hematoma (SSEH) precipitated by a coughing fit. Guided by a literature review of the risks of administering or withholding anticoagulation in this patient, doctors advised a regimen of warfarin to achieve an international normalized ratio of 1.5 to 2 and dipyridamole (75 mg qid) to protect against thromboembolic complications while minimizing the risk of recurrent SSEH.

Authors+Show Affiliations

Maingi M
Department of Medicine, University of Toronto, Ontario.
Glynn MF
No affiliation info available
Scully HE
No affiliation info available
Graham AF
No affiliation info available
Floras JS
No affiliation info available

MeSH

AnticoagulantsAortic ValveDose-Response Relationship, DrugEmbolismEpidural SpaceExerciseHeart Valve ProsthesisHematoma, Epidural, CranialHumansMaleMiddle AgedRisk FactorsSpinal DiseasesThrombosisWarfarin

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

7750040

Citation

Maingi, M, et al. "Spontaneous Spinal Epidural Hematoma in a Patient With a Mechanical Aortic Valve Taking Warfarin." The Canadian Journal of Cardiology, vol. 11, no. 5, 1995, pp. 429-32.
Maingi M, Glynn MF, Scully HE, et al. Spontaneous spinal epidural hematoma in a patient with a mechanical aortic valve taking warfarin. Can J Cardiol. 1995;11(5):429-32.
Maingi, M., Glynn, M. F., Scully, H. E., Graham, A. F., & Floras, J. S. (1995). Spontaneous spinal epidural hematoma in a patient with a mechanical aortic valve taking warfarin. The Canadian Journal of Cardiology, 11(5), 429-32.
Maingi M, et al. Spontaneous Spinal Epidural Hematoma in a Patient With a Mechanical Aortic Valve Taking Warfarin. Can J Cardiol. 1995;11(5):429-32. PubMed PMID: 7750040.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Spontaneous spinal epidural hematoma in a patient with a mechanical aortic valve taking warfarin. AU - Maingi,M, AU - Glynn,M F, AU - Scully,H E, AU - Graham,A F, AU - Floras,J S, PY - 1995/5/1/pubmed PY - 1995/5/1/medline PY - 1995/5/1/entrez SP - 429 EP - 32 JF - The Canadian journal of cardiology JO - Can J Cardiol VL - 11 IS - 5 N2 - A 59-year-old male with a mechanical aortic valve taking warfarin presented to hospital with Brown-Séquard syndrome caused by a spontaneous spinal epidural hematoma (SSEH) precipitated by a coughing fit. Guided by a literature review of the risks of administering or withholding anticoagulation in this patient, doctors advised a regimen of warfarin to achieve an international normalized ratio of 1.5 to 2 and dipyridamole (75 mg qid) to protect against thromboembolic complications while minimizing the risk of recurrent SSEH. SN - 0828-282X UR - https://www.unboundmedicine.com/medline/citation/7750040/Spontaneous_spinal_epidural_hematoma_in_a_patient_with_a_mechanical_aortic_valve_taking_warfarin_ L2 - https://medlineplus.gov/spineinjuriesanddisorders.html DB - PRIME DP - Unbound Medicine ER -