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Safety of ototopical antibiotics.
Laryngoscope 1995; 105(5 Pt 1):472-4L

Abstract

A prospective randomized study analyzing the safety and efficacy of a single dose of ototopical antibiotics following human middle ear tympanostomy tube insertion was performed. Fifty children undergoing bilateral tympanostomy tube insertion were studied by the placement of 0.5 mL of Cortisporin Otic Suspension (COS; Burroughs Wellcome Co., Research Triangle Park, N.C.) to one middle ear space by random assignment. Preoperative and postoperative audiograms were obtained, and the presence of otorrhea was noted. In one patient sensorineural hearing loss of 6 dB developed bilaterally, which was symmetric in both the treated and the untreated ear. This preliminary study showed no statistical difference in hearing loss or postoperative otorrhea associated with a single application of Cortisporin to the middle ear space.

Authors+Show Affiliations

Department of Otolaryngology, Ohio State University, Columbus, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

7760659

Citation

Welling, D B., et al. "Safety of Ototopical Antibiotics." The Laryngoscope, vol. 105, no. 5 Pt 1, 1995, pp. 472-4.
Welling DB, Forrest LA, Goll F. Safety of ototopical antibiotics. Laryngoscope. 1995;105(5 Pt 1):472-4.
Welling, D. B., Forrest, L. A., & Goll, F. (1995). Safety of ototopical antibiotics. The Laryngoscope, 105(5 Pt 1), pp. 472-4.
Welling DB, Forrest LA, Goll F. Safety of Ototopical Antibiotics. Laryngoscope. 1995;105(5 Pt 1):472-4. PubMed PMID: 7760659.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Safety of ototopical antibiotics. AU - Welling,D B, AU - Forrest,L A, AU - Goll,F,3rd PY - 1995/5/1/pubmed PY - 2001/3/28/medline PY - 1995/5/1/entrez SP - 472 EP - 4 JF - The Laryngoscope JO - Laryngoscope VL - 105 IS - 5 Pt 1 N2 - A prospective randomized study analyzing the safety and efficacy of a single dose of ototopical antibiotics following human middle ear tympanostomy tube insertion was performed. Fifty children undergoing bilateral tympanostomy tube insertion were studied by the placement of 0.5 mL of Cortisporin Otic Suspension (COS; Burroughs Wellcome Co., Research Triangle Park, N.C.) to one middle ear space by random assignment. Preoperative and postoperative audiograms were obtained, and the presence of otorrhea was noted. In one patient sensorineural hearing loss of 6 dB developed bilaterally, which was symmetric in both the treated and the untreated ear. This preliminary study showed no statistical difference in hearing loss or postoperative otorrhea associated with a single application of Cortisporin to the middle ear space. SN - 0023-852X UR - https://www.unboundmedicine.com/medline/citation/7760659/Safety_of_ototopical_antibiotics_ L2 - https://doi.org/10.1288/00005537-199505000-00003 DB - PRIME DP - Unbound Medicine ER -