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[Somatostatin plasma level in patients with liver cirrhosis].
Orv Hetil. 1995 May 28; 136(22):1163-5.OH

Abstract

The significance of changes in plasma somatostatin level at patients with vascularly decompensated liver cirrhosis was investigated. The plasma level of somatostatin, glucagon, gastrin and blood glucose concentration were determined under basal condition and after testmeal in patients with vasculary decompensated cirrhosis, in cirrhotic-patients without ascites formation and in control subjects. The basaline levels and the postprandial increases of plasma somatostatin concentrations were significantly lower in cirrhotic patients with ascites, compared to the other two groups. The glucagon concentrations--both the basaline and the postprandial--were significantly higher in the cirrhotic patients-groups, compared to the controls. The gastrin and blood glucose levels were not different in the three groups. The decrease in plasma somatostatin concentration present in cirrhosis associated with ascites represents a secondary phenomena, and suggest that endogen somatostatin plays a role in maintaining body fluid homeostasis.

Authors+Show Affiliations

Tulassay Z
Semmelweis Orvostudományi Egyetem, Budapest.
Tulassay T
No affiliation info available
Szabó A
No affiliation info available
Jaszovszky I
No affiliation info available
Gohér A
No affiliation info available

MeSH

AdultAscitesBlood GlucoseGastrinsGlucagonHumansLiver Cirrhosis, AlcoholicMaleMiddle AgedSomatostatin

Pub Type(s)

Clinical Trial
English Abstract
Journal Article

Language

hun

PubMed ID

7761079

Citation

Tulassay, Z, et al. "[Somatostatin Plasma Level in Patients With Liver Cirrhosis]." Orvosi Hetilap, vol. 136, no. 22, 1995, pp. 1163-5.
Tulassay Z, Tulassay T, Szabó A, et al. [Somatostatin plasma level in patients with liver cirrhosis]. Orv Hetil. 1995;136(22):1163-5.
Tulassay, Z., Tulassay, T., Szabó, A., Jaszovszky, I., & Gohér, A. (1995). [Somatostatin plasma level in patients with liver cirrhosis]. Orvosi Hetilap, 136(22), 1163-5.
Tulassay Z, et al. [Somatostatin Plasma Level in Patients With Liver Cirrhosis]. Orv Hetil. 1995 May 28;136(22):1163-5. PubMed PMID: 7761079.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Somatostatin plasma level in patients with liver cirrhosis]. AU - Tulassay,Z, AU - Tulassay,T, AU - Szabó,A, AU - Jaszovszky,I, AU - Gohér,A, PY - 1995/5/28/pubmed PY - 1995/5/28/medline PY - 1995/5/28/entrez SP - 1163 EP - 5 JF - Orvosi hetilap JO - Orv Hetil VL - 136 IS - 22 N2 - The significance of changes in plasma somatostatin level at patients with vascularly decompensated liver cirrhosis was investigated. The plasma level of somatostatin, glucagon, gastrin and blood glucose concentration were determined under basal condition and after testmeal in patients with vasculary decompensated cirrhosis, in cirrhotic-patients without ascites formation and in control subjects. The basaline levels and the postprandial increases of plasma somatostatin concentrations were significantly lower in cirrhotic patients with ascites, compared to the other two groups. The glucagon concentrations--both the basaline and the postprandial--were significantly higher in the cirrhotic patients-groups, compared to the controls. The gastrin and blood glucose levels were not different in the three groups. The decrease in plasma somatostatin concentration present in cirrhosis associated with ascites represents a secondary phenomena, and suggest that endogen somatostatin plays a role in maintaining body fluid homeostasis. SN - 0030-6002 UR - https://www.unboundmedicine.com/medline/citation/7761079/[Somatostatin_plasma_level_in_patients_with_liver_cirrhosis]_ DB - PRIME DP - Unbound Medicine ER -