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Antitumor active polysaccharides from the Chinese mushroom Songshan lingzhi, the fruiting body of Ganoderma tsugae.
Biosci Biotechnol Biochem. 1993 Jun; 57(6):894-900.BB

Abstract

A systematic method of extraction, fractionation, and purification of polysaccharides from Songshan Lingzhi (Ganoderma tsugae) with antitumor activity was established. Seven glycans with strong antitumor activities were obtained from 14 water-soluble, and 15 water-insoluble fractions: FIo-a, FA-1, FII-1, FIII-2, and FIII-2-a, -b, and -c. FIo-a and FA-1 were protein-containing glucogalactans associated with mannose and fucose. FII-1 was a (1-->3)-beta-D-glucan having a lower protein content. The water-insoluble fractions FIII-2-a, -b, and -c were extracted with alkali, and were found to be protein-containing (1-->3)-beta-D-glucans showing the strongest activity. Chemical properties and structure of each antitumor polysaccharide were compared with three fungi of the Ganoderma family, Kofukitake (G. applanatum), Mannentake (G. lucidum), and Songshan Lingzhi (G. tsugae).

Authors+Show Affiliations

Department of Traditional Chinese Pharmacy, Changchun College of Traditional Chinese Medicine, Jilin.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

7763875

Citation

Wang, G, et al. "Antitumor Active Polysaccharides From the Chinese Mushroom Songshan Lingzhi, the Fruiting Body of Ganoderma Tsugae." Bioscience, Biotechnology, and Biochemistry, vol. 57, no. 6, 1993, pp. 894-900.
Wang G, Zhang J, Mizuno T, et al. Antitumor active polysaccharides from the Chinese mushroom Songshan lingzhi, the fruiting body of Ganoderma tsugae. Biosci Biotechnol Biochem. 1993;57(6):894-900.
Wang, G., Zhang, J., Mizuno, T., Zhuang, C., Ito, H., Mayuzumi, H., Okamoto, H., & Li, J. (1993). Antitumor active polysaccharides from the Chinese mushroom Songshan lingzhi, the fruiting body of Ganoderma tsugae. Bioscience, Biotechnology, and Biochemistry, 57(6), 894-900.
Wang G, et al. Antitumor Active Polysaccharides From the Chinese Mushroom Songshan Lingzhi, the Fruiting Body of Ganoderma Tsugae. Biosci Biotechnol Biochem. 1993;57(6):894-900. PubMed PMID: 7763875.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antitumor active polysaccharides from the Chinese mushroom Songshan lingzhi, the fruiting body of Ganoderma tsugae. AU - Wang,G, AU - Zhang,J, AU - Mizuno,T, AU - Zhuang,C, AU - Ito,H, AU - Mayuzumi,H, AU - Okamoto,H, AU - Li,J, PY - 1993/6/1/pubmed PY - 1993/6/1/medline PY - 1993/6/1/entrez SP - 894 EP - 900 JF - Bioscience, biotechnology, and biochemistry JO - Biosci Biotechnol Biochem VL - 57 IS - 6 N2 - A systematic method of extraction, fractionation, and purification of polysaccharides from Songshan Lingzhi (Ganoderma tsugae) with antitumor activity was established. Seven glycans with strong antitumor activities were obtained from 14 water-soluble, and 15 water-insoluble fractions: FIo-a, FA-1, FII-1, FIII-2, and FIII-2-a, -b, and -c. FIo-a and FA-1 were protein-containing glucogalactans associated with mannose and fucose. FII-1 was a (1-->3)-beta-D-glucan having a lower protein content. The water-insoluble fractions FIII-2-a, -b, and -c were extracted with alkali, and were found to be protein-containing (1-->3)-beta-D-glucans showing the strongest activity. Chemical properties and structure of each antitumor polysaccharide were compared with three fungi of the Ganoderma family, Kofukitake (G. applanatum), Mannentake (G. lucidum), and Songshan Lingzhi (G. tsugae). SN - 0916-8451 UR - https://www.unboundmedicine.com/medline/citation/7763875/Antitumor_active_polysaccharides_from_the_Chinese_mushroom_Songshan_lingzhi_the_fruiting_body_of_Ganoderma_tsugae_ L2 - https://joi.jlc.jst.go.jp/JST.Journalarchive/bbb1992/57.894?lang=en&from=PubMed DB - PRIME DP - Unbound Medicine ER -