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Effects of supplemented omega-3 and omega-6 fatty acid rich oils on the cardiovascular system of thermally injured rabbits: changes in plasma and platelet fatty acids.


The effects of omega-3 fatty acid rich oil (MaxEPA oil), omega-6 fatty acid rich oil (soybean oil), and a combination of omega-3 and omega-6 oils (MaxEPA oil + soybean oil) on cardiovascular health-related parameters of thermally injured and control (sham) rabbits were determined. Plasma and platelet analyses of burned rabbits fed with MaxEPA oil revealed significantly higher concentrations of eicosapentaenoic acid and docosahexaenoic acid + myristic acid. Linolenic acid concentrations declined in animals supplemented with soybean oil + MaxEPA oil. At the end of this study the lowest concentrations of linoleic acid and arachidonic acid were found in the sham and burned groups supplemented with soybean oil + MaxEPA oil. Overall, favorable significant differences in plasma and platelet fatty acids concentrations were found in burned or sham groups supplemented with MaxEPA when compared with those of groups supplemented with soybean oil. These favorable changes in plasma and platelet lipids may have an impact on the risk of cardiovascular disease in thermally injured patients.


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    Department of Nutrition and Food Sciences, Texas Woman's University, Denton, 76204, USA.

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    The Journal of burn care & rehabilitation 16:2 Pt 1 pg 173-9; discussion 172


    Blood Platelets
    Docosahexaenoic Acids
    Drug Combinations
    Eicosapentaenoic Acid
    Fatty Acids
    Fatty Acids, Omega-3
    Myristic Acid
    Myristic Acids
    Soybean Oil
    alpha-Linolenic Acid

    Pub Type(s)

    Journal Article



    PubMed ID