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Fine needle aspiration biopsy of proliferative breast disease.
Mod Pathol. 1995 Feb; 8(2):130-6.MP

Abstract

Proliferative breast disease (PBD) is a well-recognized histologic entity that has received increasing attention in the cytologic literature. We have attempted to prospectively identify and subclassify PBD by fine needle aspiration biopsy since 1987 using criteria we developed through our experience. Over 2800 breast FNABs were performed on breast lesions from 1987 to mid-1992; 257 were cytologically diagnosed as PBD with or without atypia. Eighty-four were significantly worrisome clinically to warrant surgical excision. Forty of these were designated PBD without atypia by cytology; 23 (58%) were in agreement with histology; three (8%) were PBD with atypia by histology; five (13%) were cancers; and nine (22%) were nonproliferative. Forty-four cases were designated PBD with atypia; 24 (55%) were in agreement with the histologic diagnosis; 12 (27%) proved to be PBD without atypia; six (13%) were carcinoma; and two (5%) were nonproliferative. After 1991 we employed stricter criteria for PBD, improving on the results from 1991-1992. During this period, there were 53 diagnoses of PBD with or without atypia and 34 were excised. Nine of the 10 (90%) aspirates designated as PBD without atypia were in agreement with histologic findings. The other case was nonproliferative. Fifteen of the 24 cases diagnosed as PBD with atypia were in concordance with histologic findings (63%), one was nonproliferative, seven were PBD without atypia (29%), and one (4%) proved to be carcinoma.(

ABSTRACT

TRUNCATED AT 250 WORDS)

Authors+Show Affiliations

University of Iowa Hospital, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

7777472

Citation

Thomas, P A., et al. "Fine Needle Aspiration Biopsy of Proliferative Breast Disease." Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, vol. 8, no. 2, 1995, pp. 130-6.
Thomas PA, Cangiarella J, Raab SS, et al. Fine needle aspiration biopsy of proliferative breast disease. Mod Pathol. 1995;8(2):130-6.
Thomas, P. A., Cangiarella, J., Raab, S. S., & Waisman, J. (1995). Fine needle aspiration biopsy of proliferative breast disease. Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 8(2), 130-6.
Thomas PA, et al. Fine Needle Aspiration Biopsy of Proliferative Breast Disease. Mod Pathol. 1995;8(2):130-6. PubMed PMID: 7777472.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fine needle aspiration biopsy of proliferative breast disease. AU - Thomas,P A, AU - Cangiarella,J, AU - Raab,S S, AU - Waisman,J, PY - 1995/2/1/pubmed PY - 1995/2/1/medline PY - 1995/2/1/entrez SP - 130 EP - 6 JF - Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc JO - Mod Pathol VL - 8 IS - 2 N2 - Proliferative breast disease (PBD) is a well-recognized histologic entity that has received increasing attention in the cytologic literature. We have attempted to prospectively identify and subclassify PBD by fine needle aspiration biopsy since 1987 using criteria we developed through our experience. Over 2800 breast FNABs were performed on breast lesions from 1987 to mid-1992; 257 were cytologically diagnosed as PBD with or without atypia. Eighty-four were significantly worrisome clinically to warrant surgical excision. Forty of these were designated PBD without atypia by cytology; 23 (58%) were in agreement with histology; three (8%) were PBD with atypia by histology; five (13%) were cancers; and nine (22%) were nonproliferative. Forty-four cases were designated PBD with atypia; 24 (55%) were in agreement with the histologic diagnosis; 12 (27%) proved to be PBD without atypia; six (13%) were carcinoma; and two (5%) were nonproliferative. After 1991 we employed stricter criteria for PBD, improving on the results from 1991-1992. During this period, there were 53 diagnoses of PBD with or without atypia and 34 were excised. Nine of the 10 (90%) aspirates designated as PBD without atypia were in agreement with histologic findings. The other case was nonproliferative. Fifteen of the 24 cases diagnosed as PBD with atypia were in concordance with histologic findings (63%), one was nonproliferative, seven were PBD without atypia (29%), and one (4%) proved to be carcinoma.(ABSTRACT TRUNCATED AT 250 WORDS) SN - 0893-3952 UR - https://www.unboundmedicine.com/medline/citation/7777472/Fine_needle_aspiration_biopsy_of_proliferative_breast_disease_ L2 - https://medlineplus.gov/breastdiseases.html DB - PRIME DP - Unbound Medicine ER -