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International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods.
Eur Respir J. 1995 Mar; 8(3):483-91.ER

Abstract

The aetiology of asthma and allergic disease remains poorly understood, despite considerable research. The International Study of Asthma and Allergies in Childhood (ISAAC), was founded to maximize the value of epidemiological research into asthma and allergic disease, by establishing a standardized methodology and facilitating international collaboration. Its specific aims are: 1) to describe the prevalence and severity of asthma, rhinitis and eczema in children living in different centres, and to make comparisons within and between countries; 2) to obtain baseline measures for assessment of future trends in the prevalence and severity of these diseases; and 3) to provide a framework for further aetiological research into genetic, lifestyle, environmental, and medical care factors affecting these diseases. The ISAAC design comprises three phases. Phase 1 uses core questionnaires designed to assess the prevalence and severity of asthma and allergic disease in defined populations. Phase 2 will investigate possible aetiological factors, particularly those suggested by the findings of Phase 1. Phase 3 will be a repetition of Phase 1 to assess trends in prevalence.

Authors+Show Affiliations

Asher MI
Dept of Paediatrics, School of Medicine, University of Auckland, New Zealand.
Keil U
No affiliation info available
Anderson HR
No affiliation info available
Beasley R
No affiliation info available
Crane J
No affiliation info available
Martinez F
No affiliation info available
Mitchell EA
No affiliation info available
Pearce N
No affiliation info available
Sibbald B
No affiliation info available
Stewart AW
No affiliation info available

MeSH

AdolescentAsthmaChildData CollectionDermatitis, AtopicFemaleHumansInternational CooperationMalePrevalenceResearch DesignRhinitis, Allergic, SeasonalSurveys and Questionnaires

Pub Type(s)

Journal Article
Multicenter Study

Language

eng

PubMed ID

7789502

Clinical Trial Links

The Long-term Prognosis of Moderate to Severe Bronchial Hyperresponsiveness (BHR) in Asthmatic Preschool Children
Pulmonary Function Test, Bronchial Hyperresponsiveness and Quality of Life in Patients With Vocal Cord Dysfunction (VCD)

Citation

Asher, M I., et al. "International Study of Asthma and Allergies in Childhood (ISAAC): Rationale and Methods." The European Respiratory Journal, vol. 8, no. 3, 1995, pp. 483-91.
Asher MI, Keil U, Anderson HR, et al. International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods. Eur Respir J. 1995;8(3):483-91.
Asher, M. I., Keil, U., Anderson, H. R., Beasley, R., Crane, J., Martinez, F., Mitchell, E. A., Pearce, N., Sibbald, B., & Stewart, A. W. (1995). International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods. The European Respiratory Journal, 8(3), 483-91.
Asher MI, et al. International Study of Asthma and Allergies in Childhood (ISAAC): Rationale and Methods. Eur Respir J. 1995;8(3):483-91. PubMed PMID: 7789502.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods. A1 - Asher,M I, AU - Keil,U, AU - Anderson,H R, AU - Beasley,R, AU - Crane,J, AU - Martinez,F, AU - Mitchell,E A, AU - Pearce,N, AU - Sibbald,B, AU - Stewart,A W, PY - 1995/3/1/pubmed PY - 1995/3/1/medline PY - 1995/3/1/entrez SP - 483 EP - 91 JF - The European respiratory journal JO - Eur Respir J VL - 8 IS - 3 N2 - The aetiology of asthma and allergic disease remains poorly understood, despite considerable research. The International Study of Asthma and Allergies in Childhood (ISAAC), was founded to maximize the value of epidemiological research into asthma and allergic disease, by establishing a standardized methodology and facilitating international collaboration. Its specific aims are: 1) to describe the prevalence and severity of asthma, rhinitis and eczema in children living in different centres, and to make comparisons within and between countries; 2) to obtain baseline measures for assessment of future trends in the prevalence and severity of these diseases; and 3) to provide a framework for further aetiological research into genetic, lifestyle, environmental, and medical care factors affecting these diseases. The ISAAC design comprises three phases. Phase 1 uses core questionnaires designed to assess the prevalence and severity of asthma and allergic disease in defined populations. Phase 2 will investigate possible aetiological factors, particularly those suggested by the findings of Phase 1. Phase 3 will be a repetition of Phase 1 to assess trends in prevalence. SN - 0903-1936 UR - https://www.unboundmedicine.com/medline/citation/7789502/International_Study_of_Asthma_and_Allergies_in_Childhood__ISAAC_:_rationale_and_methods_ DB - PRIME DP - Unbound Medicine ER -