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Bacterial vaginosis: review of treatment options and potential clinical indications for therapy.
Clin Infect Dis. 1995 Apr; 20 Suppl 1:S72-9.CI

Abstract

We reviewed data on the treatment of bacterial vaginosis published from 1989 through 1992 (articles published after the 1989 publication of the Centers for Disease Control and Prevention Sexually Transmitted Diseases Treatment Guidelines). This review suggests that oral metronidazole (500 mg twice daily for 7 days) is the preferred treatment for bacterial vaginosis. Other effective (but alternative) treatment regimens include single-dose metronidazole (2 g orally), 2% clindamycin vaginal cream (once daily for 7 days), 0.75% metronidazole vaginal gel (twice daily for 5 days), and oral clindamycin (300 mg twice daily for 7 days). Data do not support the practice of routine treatment of male sex partners of infected females. Treatment of bacterial vaginosis during pregnancy should focus on the elimination of symptoms; data on adverse pregnancy outcomes for women with bacterial vaginosis remain insufficient to recommend treatment of asymptomatic patients. Before performing surgical abortion, treatment of bacterial vaginosis (symptomatic or asymptomatic) should be considered to prevent pelvic inflammatory disease.

Authors+Show Affiliations

Division of Sexually Transmitted Diseases/Human Immunodeficiency Virus Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

7795111

Citation

Joesoef, M R., and G P. Schmid. "Bacterial Vaginosis: Review of Treatment Options and Potential Clinical Indications for Therapy." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, vol. 20 Suppl 1, 1995, pp. S72-9.
Joesoef MR, Schmid GP. Bacterial vaginosis: review of treatment options and potential clinical indications for therapy. Clin Infect Dis. 1995;20 Suppl 1:S72-9.
Joesoef, M. R., & Schmid, G. P. (1995). Bacterial vaginosis: review of treatment options and potential clinical indications for therapy. Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, 20 Suppl 1, S72-9.
Joesoef MR, Schmid GP. Bacterial Vaginosis: Review of Treatment Options and Potential Clinical Indications for Therapy. Clin Infect Dis. 1995;20 Suppl 1:S72-9. PubMed PMID: 7795111.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Bacterial vaginosis: review of treatment options and potential clinical indications for therapy. AU - Joesoef,M R, AU - Schmid,G P, PY - 1995/4/1/pubmed PY - 1995/4/1/medline PY - 1995/4/1/entrez SP - S72 EP - 9 JF - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America JO - Clin. Infect. Dis. VL - 20 Suppl 1 N2 - We reviewed data on the treatment of bacterial vaginosis published from 1989 through 1992 (articles published after the 1989 publication of the Centers for Disease Control and Prevention Sexually Transmitted Diseases Treatment Guidelines). This review suggests that oral metronidazole (500 mg twice daily for 7 days) is the preferred treatment for bacterial vaginosis. Other effective (but alternative) treatment regimens include single-dose metronidazole (2 g orally), 2% clindamycin vaginal cream (once daily for 7 days), 0.75% metronidazole vaginal gel (twice daily for 5 days), and oral clindamycin (300 mg twice daily for 7 days). Data do not support the practice of routine treatment of male sex partners of infected females. Treatment of bacterial vaginosis during pregnancy should focus on the elimination of symptoms; data on adverse pregnancy outcomes for women with bacterial vaginosis remain insufficient to recommend treatment of asymptomatic patients. Before performing surgical abortion, treatment of bacterial vaginosis (symptomatic or asymptomatic) should be considered to prevent pelvic inflammatory disease. SN - 1058-4838 UR - https://www.unboundmedicine.com/medline/citation/7795111/Bacterial_vaginosis:_review_of_treatment_options_and_potential_clinical_indications_for_therapy_ L2 - https://academic.oup.com/cid/article-lookup/doi/10.1093/clinids/20.supplement_1.s72 DB - PRIME DP - Unbound Medicine ER -