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Does estimating volumetric bone density of the femoral neck improve the prediction of hip fracture? A prospective study. Study of Osteoporotic Fractures Research Group.
J Bone Miner Res. 1994 Sep; 9(9):1429-32.JB

Abstract

Standard projectional bone density of the femoral neck (BMD), defined as bone mineral content divided by the projected area of the neck, predicts hip fractures but may not accurately estimate the true volumetric bone density of the femoral neck. To determine whether an estimate of the volumetric bone density of the neck, "bone mineral apparent density" (BMAD), would be a better predictor of hip fracture, we analyzed dual x-ray absorptiometry scans obtained prospectively from 7963 older white women, of whom 83 suffered a hip fracture during follow-up. Both BMD and BMAD were stronger predictors than bone mineral content (BMC) of the femoral neck. However, BMD and BMAD had very similar predictive values for hip fracture: each standard deviation decrease in either BMD or BMAD of the femoral neck increased the age-adjusted risk of hip fracture 2.6- to 2.7-fold. We conclude that BMD and BMAD of the femoral neck have a similarly strong predictive value for hip fracture.(

ABSTRACT

TRUNCATED AT 250 WORDS)

Authors+Show Affiliations

Division of General Internal Medicine, University of California, San Francisco.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Multicenter Study
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

7817827

Citation

Cummings, S R., et al. "Does Estimating Volumetric Bone Density of the Femoral Neck Improve the Prediction of Hip Fracture? a Prospective Study. Study of Osteoporotic Fractures Research Group." Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research, vol. 9, no. 9, 1994, pp. 1429-32.
Cummings SR, Marcus R, Palermo L, et al. Does estimating volumetric bone density of the femoral neck improve the prediction of hip fracture? A prospective study. Study of Osteoporotic Fractures Research Group. J Bone Miner Res. 1994;9(9):1429-32.
Cummings, S. R., Marcus, R., Palermo, L., Ensrud, K. E., & Genant, H. K. (1994). Does estimating volumetric bone density of the femoral neck improve the prediction of hip fracture? A prospective study. Study of Osteoporotic Fractures Research Group. Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research, 9(9), 1429-32.
Cummings SR, et al. Does Estimating Volumetric Bone Density of the Femoral Neck Improve the Prediction of Hip Fracture? a Prospective Study. Study of Osteoporotic Fractures Research Group. J Bone Miner Res. 1994;9(9):1429-32. PubMed PMID: 7817827.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Does estimating volumetric bone density of the femoral neck improve the prediction of hip fracture? A prospective study. Study of Osteoporotic Fractures Research Group. AU - Cummings,S R, AU - Marcus,R, AU - Palermo,L, AU - Ensrud,K E, AU - Genant,H K, PY - 1994/9/1/pubmed PY - 1994/9/1/medline PY - 1994/9/1/entrez SP - 1429 EP - 32 JF - Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research JO - J Bone Miner Res VL - 9 IS - 9 N2 - Standard projectional bone density of the femoral neck (BMD), defined as bone mineral content divided by the projected area of the neck, predicts hip fractures but may not accurately estimate the true volumetric bone density of the femoral neck. To determine whether an estimate of the volumetric bone density of the neck, "bone mineral apparent density" (BMAD), would be a better predictor of hip fracture, we analyzed dual x-ray absorptiometry scans obtained prospectively from 7963 older white women, of whom 83 suffered a hip fracture during follow-up. Both BMD and BMAD were stronger predictors than bone mineral content (BMC) of the femoral neck. However, BMD and BMAD had very similar predictive values for hip fracture: each standard deviation decrease in either BMD or BMAD of the femoral neck increased the age-adjusted risk of hip fracture 2.6- to 2.7-fold. We conclude that BMD and BMAD of the femoral neck have a similarly strong predictive value for hip fracture.(ABSTRACT TRUNCATED AT 250 WORDS) SN - 0884-0431 UR - https://www.unboundmedicine.com/medline/citation/7817827/Does_estimating_volumetric_bone_density_of_the_femoral_neck_improve_the_prediction_of_hip_fracture_A_prospective_study__Study_of_Osteoporotic_Fractures_Research_Group_ L2 - https://doi.org/10.1002/jbmr.5650090915 DB - PRIME DP - Unbound Medicine ER -