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Androgenic effects of oral contraceptives: implications for patient compliance.
Am J Med. 1995 Jan 16; 98(1A):116S-119S.AJ

Abstract

Androgenic disorders have many negative physical effects. These effects may be caused by excess androgen (exogenous or endogenous) or by end-organ sensitivity to normal levels of androgens. Historically, androgenic progestins in oral contraceptives have also been associated with some of these negative effects. The most apparent signs of androgen excess are the external manifestations, including oily skin, acne, hirsutism, android obesity, and androgenic alopecia. Of equal concern are the potential metabolic disturbances associated with hyperandrogenicity. Unfavorable lipid profiles and increased incidence of diabetes and hypertension are very real threats to long-term health. In oral contraceptive users, external manifestations of androgenicity often lead to poor compliance, decreased efficacy, and discontinuation of oral contraceptive use, especially in the younger patient. With the introduction of the newer oral contraceptive formulations containing less androgenic progestins (norgestimate, desogestrel, gestodene), androgen-related effects have been reduced and better compliance is anticipated.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

7825631

Citation

Jones, E E.. "Androgenic Effects of Oral Contraceptives: Implications for Patient Compliance." The American Journal of Medicine, vol. 98, no. 1A, 1995, 116S-119S.
Jones EE. Androgenic effects of oral contraceptives: implications for patient compliance. Am J Med. 1995;98(1A):116S-119S.
Jones, E. E. (1995). Androgenic effects of oral contraceptives: implications for patient compliance. The American Journal of Medicine, 98(1A), 116S-119S.
Jones EE. Androgenic Effects of Oral Contraceptives: Implications for Patient Compliance. Am J Med. 1995 Jan 16;98(1A):116S-119S. PubMed PMID: 7825631.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Androgenic effects of oral contraceptives: implications for patient compliance. A1 - Jones,E E, PY - 1995/1/16/pubmed PY - 1995/1/16/medline PY - 1995/1/16/entrez KW - Androgens--side effects KW - Behavior KW - Biology KW - Contraception KW - Contraceptive Agents, Female--side effects KW - Contraceptive Agents, Progestin--side effects KW - Contraceptive Agents--side effects KW - Contraceptive Methods--side effects KW - Endocrine System KW - Family Planning KW - Hormones KW - Literature Review KW - Oral Contraceptives--side effects KW - Physiology KW - User Compliance SP - 116S EP - 119S JF - The American journal of medicine JO - Am J Med VL - 98 IS - 1A N2 - Androgenic disorders have many negative physical effects. These effects may be caused by excess androgen (exogenous or endogenous) or by end-organ sensitivity to normal levels of androgens. Historically, androgenic progestins in oral contraceptives have also been associated with some of these negative effects. The most apparent signs of androgen excess are the external manifestations, including oily skin, acne, hirsutism, android obesity, and androgenic alopecia. Of equal concern are the potential metabolic disturbances associated with hyperandrogenicity. Unfavorable lipid profiles and increased incidence of diabetes and hypertension are very real threats to long-term health. In oral contraceptive users, external manifestations of androgenicity often lead to poor compliance, decreased efficacy, and discontinuation of oral contraceptive use, especially in the younger patient. With the introduction of the newer oral contraceptive formulations containing less androgenic progestins (norgestimate, desogestrel, gestodene), androgen-related effects have been reduced and better compliance is anticipated. SN - 0002-9343 UR - https://www.unboundmedicine.com/medline/citation/7825631/Androgenic_effects_of_oral_contraceptives:_implications_for_patient_compliance_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9343(99)80069-2 DB - PRIME DP - Unbound Medicine ER -