Tags

Type your tag names separated by a space and hit enter

Partial gastric resection for peptic ulcer--comparison of the effect of variant reconstructive procedures on gastric emptying, gastric acid secretion and gastrin release in the early postoperative period II. Billroth-I gastroduodenostomy and comparison versus gastroenteroanastomotic procedures.
East Afr Med J. 1994 Jul; 71(7):414-20.EA

Abstract

Gastric emptying (GE) of a radiolabelled solid meal, gastric acid secretion and gastrin release was measured before and/or by 91/2 weeks postoperatively in 12 patients with partial gastric resection supplied with Billroth-I gastroduodenoanastomosis and usually (n = 10) with truncal vagotomy [B-1+(VT))]. The results obtained were compared to those derived from another study involving 14 patients with partial gastric resection supplied with a gastroenterostomy (of Roux-en-Y type in 11, and Billroth-II type in 3 subjects) and truncal vagotomy [Roux(B-II)+VT]. The B-I+(VT) procedure affected significantly neither the overall GE (the median T1/2 was 75 min before and 95 min after the surgery) nor the GE pattern-the median curve shape parameter S was 0.73 before and 1.07 after the operation. The basal and pentagastrin-stimulated gastric acid secretion was reduced by an average of 79% (from 8.6 +/- 2.5 to 1.8 +/- 0.5 mmol h-1, p < 0.05) and 77% (from 22.0 +/- 2.8 to 5.0 +/- 1.5 mmol h-1, p < 0.05) after the B-I+(VT), respectively. Moreover, after the B-I+(VT) a decrease in the fasted serum gastric concentration (78.3 +/- 17.0 before vs 62.4 +/- 6.9 ng l-1 after the surgery) and in the postprandial gastrin release (AUC0-120: 11716 +/- 2482 ng l-1 min before vs 9753 +/- 1183 ng l-1 min after the surgery) was found; the relevant differences were, however, statistically not significant. In patients with a preoperatively normal GE, a markedly slowed GE (T1/2 above the limit of the mean T1/2 +2SD in healthy controls) was found in 5 out of 8 (62%) patients after the Roux-en-Y procedure, and only in 1 out of 7 (14%) patients after the B-I or B-II procedure. With regard to the postoperative data, the Roux (B-II)+VT resulted in lower gastric acid secretion and gastrin release than the B-I+(VT) procedure but the relevant differences were statistically not significant.

Authors+Show Affiliations

Department of General Surgery, District Multi-Speciality Hospital, Tychy, Poland.No affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Controlled Clinical Trial
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

7828491

Citation

Lukasiewicz, S, and K Jonderko. "Partial Gastric Resection for Peptic Ulcer--comparison of the Effect of Variant Reconstructive Procedures On Gastric Emptying, Gastric Acid Secretion and Gastrin Release in the Early Postoperative Period II. Billroth-I Gastroduodenostomy and Comparison Versus Gastroenteroanastomotic Procedures." East African Medical Journal, vol. 71, no. 7, 1994, pp. 414-20.
Lukasiewicz S, Jonderko K. Partial gastric resection for peptic ulcer--comparison of the effect of variant reconstructive procedures on gastric emptying, gastric acid secretion and gastrin release in the early postoperative period II. Billroth-I gastroduodenostomy and comparison versus gastroenteroanastomotic procedures. East Afr Med J. 1994;71(7):414-20.
Lukasiewicz, S., & Jonderko, K. (1994). Partial gastric resection for peptic ulcer--comparison of the effect of variant reconstructive procedures on gastric emptying, gastric acid secretion and gastrin release in the early postoperative period II. Billroth-I gastroduodenostomy and comparison versus gastroenteroanastomotic procedures. East African Medical Journal, 71(7), 414-20.
Lukasiewicz S, Jonderko K. Partial Gastric Resection for Peptic Ulcer--comparison of the Effect of Variant Reconstructive Procedures On Gastric Emptying, Gastric Acid Secretion and Gastrin Release in the Early Postoperative Period II. Billroth-I Gastroduodenostomy and Comparison Versus Gastroenteroanastomotic Procedures. East Afr Med J. 1994;71(7):414-20. PubMed PMID: 7828491.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Partial gastric resection for peptic ulcer--comparison of the effect of variant reconstructive procedures on gastric emptying, gastric acid secretion and gastrin release in the early postoperative period II. Billroth-I gastroduodenostomy and comparison versus gastroenteroanastomotic procedures. AU - Lukasiewicz,S, AU - Jonderko,K, PY - 1994/7/1/pubmed PY - 1994/7/1/medline PY - 1994/7/1/entrez SP - 414 EP - 20 JF - East African medical journal JO - East Afr Med J VL - 71 IS - 7 N2 - Gastric emptying (GE) of a radiolabelled solid meal, gastric acid secretion and gastrin release was measured before and/or by 91/2 weeks postoperatively in 12 patients with partial gastric resection supplied with Billroth-I gastroduodenoanastomosis and usually (n = 10) with truncal vagotomy [B-1+(VT))]. The results obtained were compared to those derived from another study involving 14 patients with partial gastric resection supplied with a gastroenterostomy (of Roux-en-Y type in 11, and Billroth-II type in 3 subjects) and truncal vagotomy [Roux(B-II)+VT]. The B-I+(VT) procedure affected significantly neither the overall GE (the median T1/2 was 75 min before and 95 min after the surgery) nor the GE pattern-the median curve shape parameter S was 0.73 before and 1.07 after the operation. The basal and pentagastrin-stimulated gastric acid secretion was reduced by an average of 79% (from 8.6 +/- 2.5 to 1.8 +/- 0.5 mmol h-1, p < 0.05) and 77% (from 22.0 +/- 2.8 to 5.0 +/- 1.5 mmol h-1, p < 0.05) after the B-I+(VT), respectively. Moreover, after the B-I+(VT) a decrease in the fasted serum gastric concentration (78.3 +/- 17.0 before vs 62.4 +/- 6.9 ng l-1 after the surgery) and in the postprandial gastrin release (AUC0-120: 11716 +/- 2482 ng l-1 min before vs 9753 +/- 1183 ng l-1 min after the surgery) was found; the relevant differences were, however, statistically not significant. In patients with a preoperatively normal GE, a markedly slowed GE (T1/2 above the limit of the mean T1/2 +2SD in healthy controls) was found in 5 out of 8 (62%) patients after the Roux-en-Y procedure, and only in 1 out of 7 (14%) patients after the B-I or B-II procedure. With regard to the postoperative data, the Roux (B-II)+VT resulted in lower gastric acid secretion and gastrin release than the B-I+(VT) procedure but the relevant differences were statistically not significant. SN - 0012-835X UR - https://www.unboundmedicine.com/medline/citation/7828491/Partial_gastric_resection_for_peptic_ulcer__comparison_of_the_effect_of_variant_reconstructive_procedures_on_gastric_emptying_gastric_acid_secretion_and_gastrin_release_in_the_early_postoperative_period_II__Billroth_I_gastroduodenostomy_and_comparison_versus_gastroenteroanastomotic_procedures_ L2 - https://medlineplus.gov/pepticulcer.html DB - PRIME DP - Unbound Medicine ER -