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[Significance of cutaneous microangiopathy for the pathogenesis of dermatitis in venous congestion due to chronic venous insufficiency].
Wien Med Wochenschr. 1994; 144(10-11):206-10.WM

Abstract

Skin damage due to chronic venous insufficiency is preceded by severe microangiopathy of skin. With increasing clinical symptoms like edema, hyperpigmentation, induration, ulcer and atrophy blanche number of nutritive capillaries and transcutaneous oxygen-tension decreases, transcapillary, and interstitial leakage increases and cutaneous vascular reserve disappears. These congruent results were found by means of capillaroscopy, fluorescence-videomicroscopy, transcutaneously measured oxygen partial pressure and Laser Doppler Fluxmetry. Most of capillaries are elongated and tortuous, especially in ulcer stage they look glomerular. Compared to pin-shaped capillaries glomerular capillaries contribute less to nutrition because of functional AV-shunts. As dilated capillaries are already seen in skin areas without any trophic skin changes, cutaneous microangiopathy seems to be first consequence of venous hemodynamic disturbances which then is followed by skin disease. As severe microangiopathy still remains after healing of ulcer, it explains frequent recurrencies.

Authors+Show Affiliations

Universitäts-Hautklinik Tübingen, Deutschland.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

7856186

Citation

Jünger, M, et al. "[Significance of Cutaneous Microangiopathy for the Pathogenesis of Dermatitis in Venous Congestion Due to Chronic Venous Insufficiency]." Wiener Medizinische Wochenschrift (1946), vol. 144, no. 10-11, 1994, pp. 206-10.
Jünger M, Hahn U, Bort S, et al. [Significance of cutaneous microangiopathy for the pathogenesis of dermatitis in venous congestion due to chronic venous insufficiency]. Wien Med Wochenschr. 1994;144(10-11):206-10.
Jünger, M., Hahn, U., Bort, S., Klyscz, T., Hahn, M., & Rassner, G. (1994). [Significance of cutaneous microangiopathy for the pathogenesis of dermatitis in venous congestion due to chronic venous insufficiency]. Wiener Medizinische Wochenschrift (1946), 144(10-11), 206-10.
Jünger M, et al. [Significance of Cutaneous Microangiopathy for the Pathogenesis of Dermatitis in Venous Congestion Due to Chronic Venous Insufficiency]. Wien Med Wochenschr. 1994;144(10-11):206-10. PubMed PMID: 7856186.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Significance of cutaneous microangiopathy for the pathogenesis of dermatitis in venous congestion due to chronic venous insufficiency]. AU - Jünger,M, AU - Hahn,U, AU - Bort,S, AU - Klyscz,T, AU - Hahn,M, AU - Rassner,G, PY - 1994/1/1/pubmed PY - 1994/1/1/medline PY - 1994/1/1/entrez SP - 206 EP - 10 JF - Wiener medizinische Wochenschrift (1946) JO - Wien Med Wochenschr VL - 144 IS - 10-11 N2 - Skin damage due to chronic venous insufficiency is preceded by severe microangiopathy of skin. With increasing clinical symptoms like edema, hyperpigmentation, induration, ulcer and atrophy blanche number of nutritive capillaries and transcutaneous oxygen-tension decreases, transcapillary, and interstitial leakage increases and cutaneous vascular reserve disappears. These congruent results were found by means of capillaroscopy, fluorescence-videomicroscopy, transcutaneously measured oxygen partial pressure and Laser Doppler Fluxmetry. Most of capillaries are elongated and tortuous, especially in ulcer stage they look glomerular. Compared to pin-shaped capillaries glomerular capillaries contribute less to nutrition because of functional AV-shunts. As dilated capillaries are already seen in skin areas without any trophic skin changes, cutaneous microangiopathy seems to be first consequence of venous hemodynamic disturbances which then is followed by skin disease. As severe microangiopathy still remains after healing of ulcer, it explains frequent recurrencies. SN - 0043-5341 UR - https://www.unboundmedicine.com/medline/citation/7856186/[Significance_of_cutaneous_microangiopathy_for_the_pathogenesis_of_dermatitis_in_venous_congestion_due_to_chronic_venous_insufficiency]_ DB - PRIME DP - Unbound Medicine ER -