Oblique facial clefts: report on 4 Brazilian patients. Evidence for clinical variability and genetic heterogeneity.Am J Med Genet. 1994 Nov 15; 53(3):222-6.AJ
Oblique facial clefts are rare and include types 2-6 of Tessier's classification. Here we report on 4 patients with oblique facial clefts and a strikingly similar facial appearance. The pattern of facial involvement, the presence of consanguinity in 3 of them, as well as the entire clinical picture, suggest a unique dysmorphogenetic process which could represent, in some instances, an oculomaxillofacial dysostosis.