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Comparison of three advanced chromatographic techniques for cannabis identification.
Bull Narc. 1994; 46(2):109-21.BN

Abstract

The development of chromatography technology, with the increasing availability of easier-to-use mass spectrometers combined with gas chromatography (GC), the use of diode-array or programmable variable-wavelength ultraviolet absorption detectors in conjunction with high-performance liquid chromatography (HPLC), and the availability of scanners capable of reading thin-layer chromatography (TLC) plates in the ultraviolet and visible regions, has made for easier, quicker and more positive identification of cannabis samples that standard analytical laboratories are occasionally required to undertake in the effort to combat drug addiction. At laboratories that do not possess the technique of GC combined with mass spectrometry, which provides an irrefutable identification, the following procedure involving HPLC or TLC techniques may be used: identification of the chromatographic peaks corresponding to each of the three main cannabis constituents-cannabidiol (CBD), delta-9-tetrahydrocannabinol (delta-9-THC) and cannabinol (CBN)-by comparison with published data in conjunction with a specific absorption spectrum for each of those constituents obtained between 200 and 300 nm. The collection of the fractions corresponding to the three major cannabinoids at the HPLC system outlet and the cross-checking of their identity in the GC process with flame ionization detection can further corroborate the identification and minimize possible errors due to interference.

Authors+Show Affiliations

Drug Dependence Assessment and Information Centre, Caen Regional and University Hospital Centre, France.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

7866395

Citation

Debruyne, D, et al. "Comparison of Three Advanced Chromatographic Techniques for Cannabis Identification." Bulletin On Narcotics, vol. 46, no. 2, 1994, pp. 109-21.
Debruyne D, Albessard F, Bigot MC, et al. Comparison of three advanced chromatographic techniques for cannabis identification. Bull Narc. 1994;46(2):109-21.
Debruyne, D., Albessard, F., Bigot, M. C., & Moulin, M. (1994). Comparison of three advanced chromatographic techniques for cannabis identification. Bulletin On Narcotics, 46(2), 109-21.
Debruyne D, et al. Comparison of Three Advanced Chromatographic Techniques for Cannabis Identification. Bull Narc. 1994;46(2):109-21. PubMed PMID: 7866395.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of three advanced chromatographic techniques for cannabis identification. AU - Debruyne,D, AU - Albessard,F, AU - Bigot,M C, AU - Moulin,M, PY - 1994/1/1/pubmed PY - 1994/1/1/medline PY - 1994/1/1/entrez SP - 109 EP - 21 JF - Bulletin on narcotics JO - Bull Narc VL - 46 IS - 2 N2 - The development of chromatography technology, with the increasing availability of easier-to-use mass spectrometers combined with gas chromatography (GC), the use of diode-array or programmable variable-wavelength ultraviolet absorption detectors in conjunction with high-performance liquid chromatography (HPLC), and the availability of scanners capable of reading thin-layer chromatography (TLC) plates in the ultraviolet and visible regions, has made for easier, quicker and more positive identification of cannabis samples that standard analytical laboratories are occasionally required to undertake in the effort to combat drug addiction. At laboratories that do not possess the technique of GC combined with mass spectrometry, which provides an irrefutable identification, the following procedure involving HPLC or TLC techniques may be used: identification of the chromatographic peaks corresponding to each of the three main cannabis constituents-cannabidiol (CBD), delta-9-tetrahydrocannabinol (delta-9-THC) and cannabinol (CBN)-by comparison with published data in conjunction with a specific absorption spectrum for each of those constituents obtained between 200 and 300 nm. The collection of the fractions corresponding to the three major cannabinoids at the HPLC system outlet and the cross-checking of their identity in the GC process with flame ionization detection can further corroborate the identification and minimize possible errors due to interference. SN - 0007-523X UR - https://www.unboundmedicine.com/medline/citation/7866395/Comparison_of_three_advanced_chromatographic_techniques_for_cannabis_identification_ L2 - https://www.lens.org/lens/search/patent/list?q=citation_id:7866395 DB - PRIME DP - Unbound Medicine ER -