TY - JOUR T1 - The effect of various drugs on adenosine triphosphate content and histamine release from rat peritoneal cell suspensions rich in mast cells. AU - Day,R O, AU - Wade,D N, PY - 1978/5/1/pubmed PY - 1978/5/1/medline PY - 1978/5/1/entrez SP - 223 EP - 7 JF - Clinical and experimental pharmacology & physiology JO - Clin Exp Pharmacol Physiol VL - 5 IS - 3 N2 - 1. Iopanoic acid and iophenoxic acid were potent inhibitors of compound 48/80-induced histamine release from rat peritoneal cell suspensions rich in mast cells and caused a parallel dose-related reduction in ATP content of these cells. 2. Lignocaine was less potent and ouabain and probenecid were ineffective in inhibiting histamine release and reducing cellular ATP content. 3. Various drugs can inhibit 48/80-induced histamine release from rat peritoneal cells and this activity may result from depletion of cellular ATP. It is apparent that little structural specificity is required for activity in this cell system. SN - 0305-1870 UR - https://www.unboundmedicine.com/medline/citation/78782/The_effect_of_various_drugs_on_adenosine_triphosphate_content_and_histamine_release_from_rat_peritoneal_cell_suspensions_rich_in_mast_cells_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0305-1870&date=1978&volume=5&issue=3&spage=223 DB - PRIME DP - Unbound Medicine ER -