Tags

Type your tag names separated by a space and hit enter

Prospective study of physical activity and the risk of symptomatic diverticular disease in men.
Gut 1995; 36(2):276-82Gut

Abstract

The relationship between physical activity and risk of symptomatic diverticular disease has not been investigated directly. This association was examined in a prospective cohort of 47,678 American men, 40 to 75 years of age, and free of diagnosed diverticular disease, colon or rectal polyp, ulcerative colitis, and cancer before 1988. During four years of follow up, 382 newly diagnosed cases of symptomatic diverticular disease were documented. After adjustment for age, energy adjusted dietary fibre, and energy adjusted total fat, overall physical activity was inversely associated with the risk of symptomatic diverticular disease (for highest versus lowest extremes, relative risk (RR) = 0.63 (95% confidence interval (CI) 0.45, 0.88). Most of the inverse association was attributable to vigorous activity, for extreme categories RR = 0.60 (95% CI 0.41, 0.87). For activity that was not vigorous the RR was 0.93 (95% CI 0.67, 1.69). Several specific activities were inversely associated with the risk of diverticular disease, but jogging and running combined was the only individual activity that was statistically significant (p for trend = 0.03). For men in the lowest quintile for dietary fibre intake and total physical activity (compared with those in the opposite extreme), the RR was 2.56 (95% CI 1.36, 4.82). Physical activity, along with a high fibre diet, may be an important factor in the prevention of symptomatic diverticular disease.

Authors+Show Affiliations

Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA 02115.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

7883230

Citation

Aldoori, W H., et al. "Prospective Study of Physical Activity and the Risk of Symptomatic Diverticular Disease in Men." Gut, vol. 36, no. 2, 1995, pp. 276-82.
Aldoori WH, Giovannucci EL, Rimm EB, et al. Prospective study of physical activity and the risk of symptomatic diverticular disease in men. Gut. 1995;36(2):276-82.
Aldoori, W. H., Giovannucci, E. L., Rimm, E. B., Ascherio, A., Stampfer, M. J., Colditz, G. A., ... Willett, W. C. (1995). Prospective study of physical activity and the risk of symptomatic diverticular disease in men. Gut, 36(2), pp. 276-82.
Aldoori WH, et al. Prospective Study of Physical Activity and the Risk of Symptomatic Diverticular Disease in Men. Gut. 1995;36(2):276-82. PubMed PMID: 7883230.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prospective study of physical activity and the risk of symptomatic diverticular disease in men. AU - Aldoori,W H, AU - Giovannucci,E L, AU - Rimm,E B, AU - Ascherio,A, AU - Stampfer,M J, AU - Colditz,G A, AU - Wing,A L, AU - Trichopoulos,D V, AU - Willett,W C, PY - 1995/2/1/pubmed PY - 1995/2/1/medline PY - 1995/2/1/entrez SP - 276 EP - 82 JF - Gut JO - Gut VL - 36 IS - 2 N2 - The relationship between physical activity and risk of symptomatic diverticular disease has not been investigated directly. This association was examined in a prospective cohort of 47,678 American men, 40 to 75 years of age, and free of diagnosed diverticular disease, colon or rectal polyp, ulcerative colitis, and cancer before 1988. During four years of follow up, 382 newly diagnosed cases of symptomatic diverticular disease were documented. After adjustment for age, energy adjusted dietary fibre, and energy adjusted total fat, overall physical activity was inversely associated with the risk of symptomatic diverticular disease (for highest versus lowest extremes, relative risk (RR) = 0.63 (95% confidence interval (CI) 0.45, 0.88). Most of the inverse association was attributable to vigorous activity, for extreme categories RR = 0.60 (95% CI 0.41, 0.87). For activity that was not vigorous the RR was 0.93 (95% CI 0.67, 1.69). Several specific activities were inversely associated with the risk of diverticular disease, but jogging and running combined was the only individual activity that was statistically significant (p for trend = 0.03). For men in the lowest quintile for dietary fibre intake and total physical activity (compared with those in the opposite extreme), the RR was 2.56 (95% CI 1.36, 4.82). Physical activity, along with a high fibre diet, may be an important factor in the prevention of symptomatic diverticular disease. SN - 0017-5749 UR - https://www.unboundmedicine.com/medline/citation/7883230/full_citation L2 - http://gut.bmj.com/cgi/pmidlookup?view=long&pmid=7883230 DB - PRIME DP - Unbound Medicine ER -