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Prospective study of physical activity and the risk of symptomatic diverticular disease in men.

Abstract

The relationship between physical activity and risk of symptomatic diverticular disease has not been investigated directly. This association was examined in a prospective cohort of 47,678 American men, 40 to 75 years of age, and free of diagnosed diverticular disease, colon or rectal polyp, ulcerative colitis, and cancer before 1988. During four years of follow up, 382 newly diagnosed cases of symptomatic diverticular disease were documented. After adjustment for age, energy adjusted dietary fibre, and energy adjusted total fat, overall physical activity was inversely associated with the risk of symptomatic diverticular disease (for highest versus lowest extremes, relative risk (RR) = 0.63 (95% confidence interval (CI) 0.45, 0.88). Most of the inverse association was attributable to vigorous activity, for extreme categories RR = 0.60 (95% CI 0.41, 0.87). For activity that was not vigorous the RR was 0.93 (95% CI 0.67, 1.69). Several specific activities were inversely associated with the risk of diverticular disease, but jogging and running combined was the only individual activity that was statistically significant (p for trend = 0.03). For men in the lowest quintile for dietary fibre intake and total physical activity (compared with those in the opposite extreme), the RR was 2.56 (95% CI 1.36, 4.82). Physical activity, along with a high fibre diet, may be an important factor in the prevention of symptomatic diverticular disease.

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  • Authors+Show Affiliations

    ,

    Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA 02115.

    , , , , , , ,

    Source

    Gut 36:2 1995 Feb pg 276-82

    MeSH

    Adult
    Aged
    Body Mass Index
    Dietary Fiber
    Diverticulum, Colon
    Energy Intake
    Exercise
    Humans
    Male
    Middle Aged
    Physical Fitness
    Prospective Studies
    Risk Factors

    Pub Type(s)

    Journal Article
    Research Support, U.S. Gov't, P.H.S.

    Language

    eng

    PubMed ID

    7883230

    Citation

    Aldoori, W H., et al. "Prospective Study of Physical Activity and the Risk of Symptomatic Diverticular Disease in Men." Gut, vol. 36, no. 2, 1995, pp. 276-82.
    Aldoori WH, Giovannucci EL, Rimm EB, et al. Prospective study of physical activity and the risk of symptomatic diverticular disease in men. Gut. 1995;36(2):276-82.
    Aldoori, W. H., Giovannucci, E. L., Rimm, E. B., Ascherio, A., Stampfer, M. J., Colditz, G. A., ... Willett, W. C. (1995). Prospective study of physical activity and the risk of symptomatic diverticular disease in men. Gut, 36(2), pp. 276-82.
    Aldoori WH, et al. Prospective Study of Physical Activity and the Risk of Symptomatic Diverticular Disease in Men. Gut. 1995;36(2):276-82. PubMed PMID: 7883230.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Prospective study of physical activity and the risk of symptomatic diverticular disease in men. AU - Aldoori,W H, AU - Giovannucci,E L, AU - Rimm,E B, AU - Ascherio,A, AU - Stampfer,M J, AU - Colditz,G A, AU - Wing,A L, AU - Trichopoulos,D V, AU - Willett,W C, PY - 1995/2/1/pubmed PY - 1995/2/1/medline PY - 1995/2/1/entrez SP - 276 EP - 82 JF - Gut JO - Gut VL - 36 IS - 2 N2 - The relationship between physical activity and risk of symptomatic diverticular disease has not been investigated directly. This association was examined in a prospective cohort of 47,678 American men, 40 to 75 years of age, and free of diagnosed diverticular disease, colon or rectal polyp, ulcerative colitis, and cancer before 1988. During four years of follow up, 382 newly diagnosed cases of symptomatic diverticular disease were documented. After adjustment for age, energy adjusted dietary fibre, and energy adjusted total fat, overall physical activity was inversely associated with the risk of symptomatic diverticular disease (for highest versus lowest extremes, relative risk (RR) = 0.63 (95% confidence interval (CI) 0.45, 0.88). Most of the inverse association was attributable to vigorous activity, for extreme categories RR = 0.60 (95% CI 0.41, 0.87). For activity that was not vigorous the RR was 0.93 (95% CI 0.67, 1.69). Several specific activities were inversely associated with the risk of diverticular disease, but jogging and running combined was the only individual activity that was statistically significant (p for trend = 0.03). For men in the lowest quintile for dietary fibre intake and total physical activity (compared with those in the opposite extreme), the RR was 2.56 (95% CI 1.36, 4.82). Physical activity, along with a high fibre diet, may be an important factor in the prevention of symptomatic diverticular disease. SN - 0017-5749 UR - https://www.unboundmedicine.com/medline/citation/7883230/full_citation L2 - http://gut.bmj.com/cgi/pmidlookup?view=long&pmid=7883230 DB - PRIME DP - Unbound Medicine ER -