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Experience with amphotericin B in sodium stibogluconate--unresponsive cases of visceral Leishmaniasis in north Bihar.
J Assoc Physicians India. 1994 Sep; 42(9):690-1.JA

Abstract

One hundred cases of Indian Kala-azar unresponsive to sodium stibogluconate (SSG) were treated with amphotericin B. The drug was given in the dose schedule of 0.75 mg/kg body weight on alternate days intravenously dissolved in 5 percent dextrose solution. After 15 infusions given over a period of 30 days, all cases became clinically and parasitologically cured. Mild adverse reactions were noted during therapy. No relapse was observed at follow up after 12 months.

Authors+Show Affiliations

Giri OP
Department of Medicine, Darbhanga Medical College and Hospital, Laheriasaral, Darbhanga.
Singh AN
No affiliation info available

MeSH

AdolescentAdultAmphotericin BAntimony Sodium GluconateDrug ResistanceFemaleHumansIndiaLeishmaniasis, VisceralMaleMiddle Aged

Pub Type(s)

Clinical Trial
Journal Article

Language

eng

PubMed ID

7883660

Citation

Giri, O P., and A N. Singh. "Experience With Amphotericin B in Sodium Stibogluconate--unresponsive Cases of Visceral Leishmaniasis in North Bihar." The Journal of the Association of Physicians of India, vol. 42, no. 9, 1994, pp. 690-1.
Giri OP, Singh AN. Experience with amphotericin B in sodium stibogluconate--unresponsive cases of visceral Leishmaniasis in north Bihar. J Assoc Physicians India. 1994;42(9):690-1.
Giri, O. P., & Singh, A. N. (1994). Experience with amphotericin B in sodium stibogluconate--unresponsive cases of visceral Leishmaniasis in north Bihar. The Journal of the Association of Physicians of India, 42(9), 690-1.
Giri OP, Singh AN. Experience With Amphotericin B in Sodium Stibogluconate--unresponsive Cases of Visceral Leishmaniasis in North Bihar. J Assoc Physicians India. 1994;42(9):690-1. PubMed PMID: 7883660.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Experience with amphotericin B in sodium stibogluconate--unresponsive cases of visceral Leishmaniasis in north Bihar. AU - Giri,O P, AU - Singh,A N, PY - 1994/9/1/pubmed PY - 1994/9/1/medline PY - 1994/9/1/entrez SP - 690 EP - 1 JF - The Journal of the Association of Physicians of India JO - J Assoc Physicians India VL - 42 IS - 9 N2 - One hundred cases of Indian Kala-azar unresponsive to sodium stibogluconate (SSG) were treated with amphotericin B. The drug was given in the dose schedule of 0.75 mg/kg body weight on alternate days intravenously dissolved in 5 percent dextrose solution. After 15 infusions given over a period of 30 days, all cases became clinically and parasitologically cured. Mild adverse reactions were noted during therapy. No relapse was observed at follow up after 12 months. SN - 0004-5772 UR - https://www.unboundmedicine.com/medline/citation/7883660/Experience_with_amphotericin_B_in_sodium_stibogluconate__unresponsive_cases_of_visceral_Leishmaniasis_in_north_Bihar_ L2 - http://www.diseaseinfosearch.org/result/4166 DB - PRIME DP - Unbound Medicine ER -