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[Ebastine vs terfenadine in allergic rhinitis].
Rev Alerg. 1993 Jul-Aug; 40(4):82-5.RA

Abstract

A prospective, comparative, random study was conducted with 40 patients treated with ebastine vs. terfenadine. The purpose of the study was to evaluate the efficacy of both as second generation antihistamines used in the treatment of allergic rhinitis. Ten milligrams of ebastine was administered once a day before breakfast (fasting), in 5 and 10 year old children and 20 mg in 11 to 15 year olds. Ebastine was more efficient in the control of symptoms (rhinorrhea, nasal obstruction, sneezing, eye and nose itching) than terfenadine from the seventh day on, (p 0.05). Tolerance to ebastine was good, although a small number of patients (1.5%) suffered collateral symptoms: sleepiness, headaches and nausea. The two doses of ebastine (10 or 20 mg depending on the patients age) had overall efficacy rates better than terfenadine (p 0.05%).

Authors+Show Affiliations

Laboratorio de inmunologia e histocompatibilidad INER, SS.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
English Abstract
Journal Article
Randomized Controlled Trial

Language

spa

PubMed ID

7908244

Citation

Terán Ortíz, L, et al. "[Ebastine Vs Terfenadine in Allergic Rhinitis]." Revista Alergia : Organo Oficial De La Sociedad Mexicana De Alergia E Inmunlogia, vol. 40, no. 4, 1993, pp. 82-5.
Terán Ortíz L, Flores Sandoval G, Orea Solano M, et al. [Ebastine vs terfenadine in allergic rhinitis]. Rev Alerg. 1993;40(4):82-5.
Terán Ortíz, L., Flores Sandoval, G., Orea Solano, M., & Camarena, A. (1993). [Ebastine vs terfenadine in allergic rhinitis]. Revista Alergia : Organo Oficial De La Sociedad Mexicana De Alergia E Inmunlogia, 40(4), 82-5.
Terán Ortíz L, et al. [Ebastine Vs Terfenadine in Allergic Rhinitis]. Rev Alerg. 1993 Jul-Aug;40(4):82-5. PubMed PMID: 7908244.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Ebastine vs terfenadine in allergic rhinitis]. AU - Terán Ortíz,L, AU - Flores Sandoval,G, AU - Orea Solano,M, AU - Camarena,A, PY - 1993/7/1/pubmed PY - 1993/7/1/medline PY - 1993/7/1/entrez SP - 82 EP - 5 JF - Revista alergia : organo oficial de la Sociedad Mexicana de Alergia e Inmunlogia JO - Rev Alerg VL - 40 IS - 4 N2 - A prospective, comparative, random study was conducted with 40 patients treated with ebastine vs. terfenadine. The purpose of the study was to evaluate the efficacy of both as second generation antihistamines used in the treatment of allergic rhinitis. Ten milligrams of ebastine was administered once a day before breakfast (fasting), in 5 and 10 year old children and 20 mg in 11 to 15 year olds. Ebastine was more efficient in the control of symptoms (rhinorrhea, nasal obstruction, sneezing, eye and nose itching) than terfenadine from the seventh day on, (p 0.05). Tolerance to ebastine was good, although a small number of patients (1.5%) suffered collateral symptoms: sleepiness, headaches and nausea. The two doses of ebastine (10 or 20 mg depending on the patients age) had overall efficacy rates better than terfenadine (p 0.05%). UR - https://www.unboundmedicine.com/medline/citation/7908244/[Ebastine_vs_terfenadine_in_allergic_rhinitis]_ L2 - http://www.diseaseinfosearch.org/result/7665 DB - PRIME DP - Unbound Medicine ER -