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Cutaneous disease and alcohol misuse.

Abstract

Certain skin disorders have now been demonstrated to be affected by alcohol misuse, in particular psoriasis and discoid eczema. The pattern of involvement in psoriasis differs from psoriasis vulgaris in character and distribution, and tends to be more difficult to treat. Discoid eczema appears to be specifically related to alcohol excess and is associated with deranged liver function tests. Rosacea, post-adolescent acne, superficial infections and porphyria cutanea tarda may also be markers of alcohol misuse. These disorders occur early and are quite distinct from the traditional cutaneous stigmata of established liver disease. The association between alcohol and skin disease is under-reported, as alcohol misuse may go undetected in a general clinic unless specifically sought. Alcohol has a profound influence on immune function and induces changes in the cutaneous vasculature. The relevance of these effects to the pathophysiology of alcohol-related skin disease is discussed.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Dermatology, King's College Hospital, London, UK.

    Source

    British medical bulletin 50:1 1994 Jan pg 85-98

    MeSH

    Alcohol Drinking
    Alcoholism
    Eczema
    Flushing
    Humans
    Liver Diseases, Alcoholic
    Porphyria Cutanea Tarda
    Psoriasis
    Rosacea
    Skin Diseases

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    7908595

    Citation

    Higgins, E M., and A W. du Vivier. "Cutaneous Disease and Alcohol Misuse." British Medical Bulletin, vol. 50, no. 1, 1994, pp. 85-98.
    Higgins EM, du Vivier AW. Cutaneous disease and alcohol misuse. Br Med Bull. 1994;50(1):85-98.
    Higgins, E. M., & du Vivier, A. W. (1994). Cutaneous disease and alcohol misuse. British Medical Bulletin, 50(1), pp. 85-98.
    Higgins EM, du Vivier AW. Cutaneous Disease and Alcohol Misuse. Br Med Bull. 1994;50(1):85-98. PubMed PMID: 7908595.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Cutaneous disease and alcohol misuse. AU - Higgins,E M, AU - du Vivier,A W, PY - 1994/1/1/pubmed PY - 1994/1/1/medline PY - 1994/1/1/entrez SP - 85 EP - 98 JF - British medical bulletin JO - Br. Med. Bull. VL - 50 IS - 1 N2 - Certain skin disorders have now been demonstrated to be affected by alcohol misuse, in particular psoriasis and discoid eczema. The pattern of involvement in psoriasis differs from psoriasis vulgaris in character and distribution, and tends to be more difficult to treat. Discoid eczema appears to be specifically related to alcohol excess and is associated with deranged liver function tests. Rosacea, post-adolescent acne, superficial infections and porphyria cutanea tarda may also be markers of alcohol misuse. These disorders occur early and are quite distinct from the traditional cutaneous stigmata of established liver disease. The association between alcohol and skin disease is under-reported, as alcohol misuse may go undetected in a general clinic unless specifically sought. Alcohol has a profound influence on immune function and induces changes in the cutaneous vasculature. The relevance of these effects to the pathophysiology of alcohol-related skin disease is discussed. SN - 0007-1420 UR - https://www.unboundmedicine.com/medline/citation/7908595/Cutaneous_disease_and_alcohol_misuse_ L2 - https://academic.oup.com/bmb/article-lookup/doi/10.1093/oxfordjournals.bmb.a072887 DB - PRIME DP - Unbound Medicine ER -