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Vitamin E in the treatment of tardive dyskinesia.
J Postgrad Med. 1993 Jul-Sep; 39(3):124-6.JP

Abstract

In a double-blind placebo controlled trial, the efficacy of Vitamin E in the treatment of tardive dyskinesia (TD) was studied in 32 patients. After a two week wash-out phase a baseline (0 week) TD rating was assessed on the tardive dyskinesia rating scale (TDRS). Subsequently, the patients entered a four week treatment phase during which 17 patients received capsules of vitamin E (600 mg) and 15 patients received identical placebo capsules. In the first week the patients received 1 capsule daily which was then increased to two capsules per day from the second to the fourth week. All patients were rated on the TDRS at the end of each week. The baseline TDRS score in the vitamin E group was significantly higher than the placebo group. This was hence adjusted and the results were then subjected to analysis of co- variance. The TDRS score after four weeks treatment was significantly lower in the vitamin E group as compared to the placebo group (p = 0.03).

Authors+Show Affiliations

Central Institute of Psychiatry, Ranchi, Bihar.No affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

7914238

Citation

Akhtar, S, et al. "Vitamin E in the Treatment of Tardive Dyskinesia." Journal of Postgraduate Medicine, vol. 39, no. 3, 1993, pp. 124-6.
Akhtar S, Jajor TR, Kumar S. Vitamin E in the treatment of tardive dyskinesia. J Postgrad Med. 1993;39(3):124-6.
Akhtar, S., Jajor, T. R., & Kumar, S. (1993). Vitamin E in the treatment of tardive dyskinesia. Journal of Postgraduate Medicine, 39(3), 124-6.
Akhtar S, Jajor TR, Kumar S. Vitamin E in the Treatment of Tardive Dyskinesia. J Postgrad Med. 1993;39(3):124-6. PubMed PMID: 7914238.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Vitamin E in the treatment of tardive dyskinesia. AU - Akhtar,S, AU - Jajor,T R, AU - Kumar,S, PY - 1993/7/1/pubmed PY - 1993/7/1/medline PY - 1993/7/1/entrez SP - 124 EP - 6 JF - Journal of postgraduate medicine JO - J Postgrad Med VL - 39 IS - 3 N2 - In a double-blind placebo controlled trial, the efficacy of Vitamin E in the treatment of tardive dyskinesia (TD) was studied in 32 patients. After a two week wash-out phase a baseline (0 week) TD rating was assessed on the tardive dyskinesia rating scale (TDRS). Subsequently, the patients entered a four week treatment phase during which 17 patients received capsules of vitamin E (600 mg) and 15 patients received identical placebo capsules. In the first week the patients received 1 capsule daily which was then increased to two capsules per day from the second to the fourth week. All patients were rated on the TDRS at the end of each week. The baseline TDRS score in the vitamin E group was significantly higher than the placebo group. This was hence adjusted and the results were then subjected to analysis of co- variance. The TDRS score after four weeks treatment was significantly lower in the vitamin E group as compared to the placebo group (p = 0.03). SN - 0022-3859 UR - https://www.unboundmedicine.com/medline/citation/7914238/Vitamin_E_in_the_treatment_of_tardive_dyskinesia_ L2 - http://www.jpgmonline.com/article.asp?issn=0022-3859;year=1993;volume=39;issue=3;spage=124;epage=6;aulast=Akhtar DB - PRIME DP - Unbound Medicine ER -