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Absence of neuroleptic-induced parkinsonism in psychotic patients receiving adjunctive electroconvulsive therapy.
Convuls Ther. 1994 Mar; 10(1):53-8.CT

Abstract

The presence of movement disorders was ascertained blind to treatment status in 35 schizophrenic patients. All were on neuroleptics and receiving, or had received earlier during the index episode, adjunctive bilateral electroconvulsive therapy (ECT). None manifested signs of neuroleptic-induced parkinsonism (rigidity, bradykinesia, or abnormal gait). Fine tremor of the hands was noted in two patients, and only one met criteria for probable mild tardive dyskinesia. The implications of these findings for understanding neurological complications associated with schizophrenia and its treatment with ECT are discussed. The hypothesis is proposed that ECT protects against neuroleptic-induced parkinsonism and thereby may reduce the risk for the subsequent development of tardive dyskinesia.

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Authors+Show Affiliations

Mukherjee S
Department of Psychiatry, Medical College of Georgia, Augusta 30912-3800.
Debsikdar V
No affiliation info available

MeSH

Acute DiseaseAdultAntipsychotic AgentsDyskinesia, Drug-InducedElectroconvulsive TherapyFemaleHumansMaleMiddle AgedParkinson Disease, SecondarySchizophreniaSingle-Blind Method

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

7914462

Citation

Mukherjee, S, and V Debsikdar. "Absence of Neuroleptic-induced Parkinsonism in Psychotic Patients Receiving Adjunctive Electroconvulsive Therapy." Convulsive Therapy, vol. 10, no. 1, 1994, pp. 53-8.
Mukherjee S, Debsikdar V. Absence of neuroleptic-induced parkinsonism in psychotic patients receiving adjunctive electroconvulsive therapy. Convuls Ther. 1994;10(1):53-8.
Mukherjee, S., & Debsikdar, V. (1994). Absence of neuroleptic-induced parkinsonism in psychotic patients receiving adjunctive electroconvulsive therapy. Convulsive Therapy, 10(1), 53-8.
Mukherjee S, Debsikdar V. Absence of Neuroleptic-induced Parkinsonism in Psychotic Patients Receiving Adjunctive Electroconvulsive Therapy. Convuls Ther. 1994;10(1):53-8. PubMed PMID: 7914462.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Absence of neuroleptic-induced parkinsonism in psychotic patients receiving adjunctive electroconvulsive therapy. AU - Mukherjee,S, AU - Debsikdar,V, PY - 1994/3/1/pubmed PY - 1994/3/1/medline PY - 1994/3/1/entrez SP - 53 EP - 8 JF - Convulsive therapy JO - Convuls Ther VL - 10 IS - 1 N2 - The presence of movement disorders was ascertained blind to treatment status in 35 schizophrenic patients. All were on neuroleptics and receiving, or had received earlier during the index episode, adjunctive bilateral electroconvulsive therapy (ECT). None manifested signs of neuroleptic-induced parkinsonism (rigidity, bradykinesia, or abnormal gait). Fine tremor of the hands was noted in two patients, and only one met criteria for probable mild tardive dyskinesia. The implications of these findings for understanding neurological complications associated with schizophrenia and its treatment with ECT are discussed. The hypothesis is proposed that ECT protects against neuroleptic-induced parkinsonism and thereby may reduce the risk for the subsequent development of tardive dyskinesia. SN - 0749-8055 UR - https://www.unboundmedicine.com/medline/citation/7914462/Absence_of_neuroleptic_induced_parkinsonism_in_psychotic_patients_receiving_adjunctive_electroconvulsive_therapy_ L2 - https://Insights.ovid.com/pubmed?pmid=7914462 DB - PRIME DP - Unbound Medicine ER -