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Gastrointestinal dysfunction in Parkinson's disease. A report of clinical experience at a single center.
J Clin Gastroenterol. 1994 Jul; 19(1):11-6.JC

Abstract

We describe our clinical experience in the evaluation of gastrointestinal symptoms in patients with Parkinson's disease. Dysphagia, heartburn, medication-related nausea, and constipation were the predominant symptoms. Although all of the patients localized their dysphagia to the oropharynx and although oropharyngeal dysfunction was common, evaluation revealed significant dysfunction in either the esophageal body or lower esophageal sphincter in many--gastroesophageal reflux-related disease being especially common. Studies of anorectal sphincter and pelvic floor function in those patients with constipation demonstrated a high incidence of abnormal external anal sphincter dysfunction. We conclude, first, that dysphagia in patients with Parkinson's disease should not be assumed to result solely from oropharyngeal dysfunction but deserves detailed evaluation and, second, that constipation in Parkinson's disease is commonly consequent on anorectal sphincter and pelvic floor dysfunction.

Authors+Show Affiliations

Department of Internal Medicine, University of Nebraska Medical Center, Omaha.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

7930424

Citation

Byrne, K G., et al. "Gastrointestinal Dysfunction in Parkinson's Disease. a Report of Clinical Experience at a Single Center." Journal of Clinical Gastroenterology, vol. 19, no. 1, 1994, pp. 11-6.
Byrne KG, Pfeiffer R, Quigley EM. Gastrointestinal dysfunction in Parkinson's disease. A report of clinical experience at a single center. J Clin Gastroenterol. 1994;19(1):11-6.
Byrne, K. G., Pfeiffer, R., & Quigley, E. M. (1994). Gastrointestinal dysfunction in Parkinson's disease. A report of clinical experience at a single center. Journal of Clinical Gastroenterology, 19(1), 11-6.
Byrne KG, Pfeiffer R, Quigley EM. Gastrointestinal Dysfunction in Parkinson's Disease. a Report of Clinical Experience at a Single Center. J Clin Gastroenterol. 1994;19(1):11-6. PubMed PMID: 7930424.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Gastrointestinal dysfunction in Parkinson's disease. A report of clinical experience at a single center. AU - Byrne,K G, AU - Pfeiffer,R, AU - Quigley,E M, PY - 1994/7/1/pubmed PY - 1994/7/1/medline PY - 1994/7/1/entrez SP - 11 EP - 6 JF - Journal of clinical gastroenterology JO - J. Clin. Gastroenterol. VL - 19 IS - 1 N2 - We describe our clinical experience in the evaluation of gastrointestinal symptoms in patients with Parkinson's disease. Dysphagia, heartburn, medication-related nausea, and constipation were the predominant symptoms. Although all of the patients localized their dysphagia to the oropharynx and although oropharyngeal dysfunction was common, evaluation revealed significant dysfunction in either the esophageal body or lower esophageal sphincter in many--gastroesophageal reflux-related disease being especially common. Studies of anorectal sphincter and pelvic floor function in those patients with constipation demonstrated a high incidence of abnormal external anal sphincter dysfunction. We conclude, first, that dysphagia in patients with Parkinson's disease should not be assumed to result solely from oropharyngeal dysfunction but deserves detailed evaluation and, second, that constipation in Parkinson's disease is commonly consequent on anorectal sphincter and pelvic floor dysfunction. SN - 0192-0790 UR - https://www.unboundmedicine.com/medline/citation/7930424/Gastrointestinal_dysfunction_in_Parkinson's_disease__A_report_of_clinical_experience_at_a_single_center_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=7930424.ui DB - PRIME DP - Unbound Medicine ER -