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Dermatologic and systemic manifestations of syphilis.
Am Fam Physician. 1994 Oct; 50(5):1013-20.AF

Abstract

The incidence of syphilis is increasing, predominantly among urban heterosexuals. Early recognition is important in preventing progression of the disease and transmission of Treponema pallidum to the fetus. Untreated primary syphilis is characterized by intervals of active disease punctuated by periods of latency. Not all patients progress through each phase, and the physician must be alert to varying presentations. Cutaneous lesions are the hallmark of syphilis. However, diagnosis can be difficult, because the lesions can be asymptomatic or transient. The course of syphilis is accelerated in patients infected with the human immunodeficiency virus, and these patients frequently exhibit atypical lesions. The incidence of congenital syphilis is increasing, and efforts to control fetal morbidity depend on prompt recognition and treatment of infection during pregnancy. The definitive diagnosis of any stage of syphilis is based on historical and clinical findings supported by serologic testing.

Authors+Show Affiliations

Free University of Brussels, Belgium.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

7942400

Citation

Goens, J L., et al. "Dermatologic and Systemic Manifestations of Syphilis." American Family Physician, vol. 50, no. 5, 1994, pp. 1013-20.
Goens JL, Janniger CK, De Wolf K. Dermatologic and systemic manifestations of syphilis. Am Fam Physician. 1994;50(5):1013-20.
Goens, J. L., Janniger, C. K., & De Wolf, K. (1994). Dermatologic and systemic manifestations of syphilis. American Family Physician, 50(5), 1013-20.
Goens JL, Janniger CK, De Wolf K. Dermatologic and Systemic Manifestations of Syphilis. Am Fam Physician. 1994;50(5):1013-20. PubMed PMID: 7942400.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dermatologic and systemic manifestations of syphilis. AU - Goens,J L, AU - Janniger,C K, AU - De Wolf,K, PY - 1994/10/1/pubmed PY - 1994/10/1/medline PY - 1994/10/1/entrez SP - 1013 EP - 20 JF - American family physician JO - Am Fam Physician VL - 50 IS - 5 N2 - The incidence of syphilis is increasing, predominantly among urban heterosexuals. Early recognition is important in preventing progression of the disease and transmission of Treponema pallidum to the fetus. Untreated primary syphilis is characterized by intervals of active disease punctuated by periods of latency. Not all patients progress through each phase, and the physician must be alert to varying presentations. Cutaneous lesions are the hallmark of syphilis. However, diagnosis can be difficult, because the lesions can be asymptomatic or transient. The course of syphilis is accelerated in patients infected with the human immunodeficiency virus, and these patients frequently exhibit atypical lesions. The incidence of congenital syphilis is increasing, and efforts to control fetal morbidity depend on prompt recognition and treatment of infection during pregnancy. The definitive diagnosis of any stage of syphilis is based on historical and clinical findings supported by serologic testing. SN - 0002-838X UR - https://www.unboundmedicine.com/medline/citation/7942400/Dermatologic_and_systemic_manifestations_of_syphilis_ L2 - https://medlineplus.gov/syphilis.html DB - PRIME DP - Unbound Medicine ER -
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