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Oral challenges to detect aspirin and sulfite sensitivity in asthma.
Allerg Immunol (Paris). 1994 Jun; 26(6):216-8.AI

Abstract

Oral challenge with aspirin or potential cross-reacting substances (including other nonsteroidal anti-inflammatory drugs [NSAIDs] or food and drug additives) is an effective method for establishing the presence of sensitivity to these substances in asthmatic subjects. Sulfite challenges can be performed in a similar manner. However, many of these subjects have concomitant active irritable airways that could make testing both inaccurate and potentially dangerous. This paper contains strategies for dealing with these problems as well as other important details in conducting oral challenges in asthmatic subjects in a manner which will lead to valid data and conclusions.

Authors+Show Affiliations

Department of Allergy, Scripps Clinic and Research Foundation, La Jolla, California.

Pub Type(s)

Clinical Trial
Comparative Study
Controlled Clinical Trial
Journal Article

Language

eng

PubMed ID

7945787

Citation

Simon, R A.. "Oral Challenges to Detect Aspirin and Sulfite Sensitivity in Asthma." Allergie Et Immunologie, vol. 26, no. 6, 1994, pp. 216-8.
Simon RA. Oral challenges to detect aspirin and sulfite sensitivity in asthma. Allerg Immunol (Paris). 1994;26(6):216-8.
Simon, R. A. (1994). Oral challenges to detect aspirin and sulfite sensitivity in asthma. Allergie Et Immunologie, 26(6), 216-8.
Simon RA. Oral Challenges to Detect Aspirin and Sulfite Sensitivity in Asthma. Allerg Immunol (Paris). 1994;26(6):216-8. PubMed PMID: 7945787.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Oral challenges to detect aspirin and sulfite sensitivity in asthma. A1 - Simon,R A, PY - 1994/6/1/pubmed PY - 1994/6/1/medline PY - 1994/6/1/entrez SP - 216 EP - 8 JF - Allergie et immunologie JO - Allerg Immunol (Paris) VL - 26 IS - 6 N2 - Oral challenge with aspirin or potential cross-reacting substances (including other nonsteroidal anti-inflammatory drugs [NSAIDs] or food and drug additives) is an effective method for establishing the presence of sensitivity to these substances in asthmatic subjects. Sulfite challenges can be performed in a similar manner. However, many of these subjects have concomitant active irritable airways that could make testing both inaccurate and potentially dangerous. This paper contains strategies for dealing with these problems as well as other important details in conducting oral challenges in asthmatic subjects in a manner which will lead to valid data and conclusions. SN - 0397-9148 UR - https://www.unboundmedicine.com/medline/citation/7945787/Oral_challenges_to_detect_aspirin_and_sulfite_sensitivity_in_asthma_ L2 - http://www.diseaseinfosearch.org/result/633 DB - PRIME DP - Unbound Medicine ER -