Tags

Type your tag names separated by a space and hit enter

Vascular-laboratory diagnosis of clinically suspected acute deep-vein thrombosis.
Lancet. 1978 Aug 12; 2(8085):331-4.Lct

Abstract

Doppler ultrasound, impedance plethysmography, and contrast venography were performed in 207 lower limbs suspected of harbouring deep-venous thrombosis, to clarify the diagnostic value and limitations of the non-invasive methods. Doppler ultrasound and impedance plethysmography were accurate in 96% and 95% of normal limbs, respectively. In limbs with venographic evidence of thrombosis requiring treatment, Dopper ultrasound and impedance plethysmography correctly detected thrombosis in 60% and 97%, respectively. Doppler ultrasound was 97% accurate in recognising chronic venous insufficiency. Impedance plethysmography was incorrectly positive in 74% of limbs with chronic venous insufficienv cy which had no venographically detected thrombosis. These findings suggest that, for the accurate diagnosis of clinically suspected deep-vein thrombosis, venography is necessary only in patients with chronic venous insufficiency who have normal Doppler ultrasound tests and abnormal impedance plethysmograms and in patients with abnormal cardiac haemodynamics. In this series, 86% of limbs would have been spared venography had non-invasive tests been used. Venography, however, remains the standard test for the detection of minor calf-vein thrombosis. A diagnostic and therapeutic schema is proposed.

Links

Publisher Full Text

Authors

Flanigan DP
No affiliation info available
Goodreau JJ
No affiliation info available
Burnham SJ
No affiliation info available
Bergan JJ
No affiliation info available
Yao JS
No affiliation info available

MeSH

Chronic DiseaseDoppler EffectEvaluation Studies as TopicFalse Positive ReactionsHumansLegPhlebographyPlethysmography, ImpedanceThrombophlebitisUltrasonographyVenous Insufficiency

Pub Type(s)

Clinical Trial
Comparative Study
Controlled Clinical Trial
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

79707

Citation

Flanigan, D P., et al. "Vascular-laboratory Diagnosis of Clinically Suspected Acute Deep-vein Thrombosis." Lancet (London, England), vol. 2, no. 8085, 1978, pp. 331-4.
Flanigan DP, Goodreau JJ, Burnham SJ, et al. Vascular-laboratory diagnosis of clinically suspected acute deep-vein thrombosis. Lancet. 1978;2(8085):331-4.
Flanigan, D. P., Goodreau, J. J., Burnham, S. J., Bergan, J. J., & Yao, J. S. (1978). Vascular-laboratory diagnosis of clinically suspected acute deep-vein thrombosis. Lancet (London, England), 2(8085), 331-4.
Flanigan DP, et al. Vascular-laboratory Diagnosis of Clinically Suspected Acute Deep-vein Thrombosis. Lancet. 1978 Aug 12;2(8085):331-4. PubMed PMID: 79707.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Vascular-laboratory diagnosis of clinically suspected acute deep-vein thrombosis. AU - Flanigan,D P, AU - Goodreau,J J, AU - Burnham,S J, AU - Bergan,J J, AU - Yao,J S, PY - 1978/8/12/pubmed PY - 1978/8/12/medline PY - 1978/8/12/entrez SP - 331 EP - 4 JF - Lancet (London, England) JO - Lancet VL - 2 IS - 8085 N2 - Doppler ultrasound, impedance plethysmography, and contrast venography were performed in 207 lower limbs suspected of harbouring deep-venous thrombosis, to clarify the diagnostic value and limitations of the non-invasive methods. Doppler ultrasound and impedance plethysmography were accurate in 96% and 95% of normal limbs, respectively. In limbs with venographic evidence of thrombosis requiring treatment, Dopper ultrasound and impedance plethysmography correctly detected thrombosis in 60% and 97%, respectively. Doppler ultrasound was 97% accurate in recognising chronic venous insufficiency. Impedance plethysmography was incorrectly positive in 74% of limbs with chronic venous insufficienv cy which had no venographically detected thrombosis. These findings suggest that, for the accurate diagnosis of clinically suspected deep-vein thrombosis, venography is necessary only in patients with chronic venous insufficiency who have normal Doppler ultrasound tests and abnormal impedance plethysmograms and in patients with abnormal cardiac haemodynamics. In this series, 86% of limbs would have been spared venography had non-invasive tests been used. Venography, however, remains the standard test for the detection of minor calf-vein thrombosis. A diagnostic and therapeutic schema is proposed. SN - 0140-6736 UR - https://www.unboundmedicine.com/medline/citation/79707/Vascular_laboratory_diagnosis_of_clinically_suspected_acute_deep_vein_thrombosis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0140-6736(78)92939-2 DB - PRIME DP - Unbound Medicine ER -