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Meta-analysis of highly selective vagotomy versus truncal vagotomy and pyloroplasty in the surgical treatment of uncomplicated duodenal ulcer.
Can J Surg. 1994 Dec; 37(6):457-64.CJ

Abstract

OBJECTIVE

To compare critically by meta-analysis the postoperative outcomes after truncal vagotomy and pyloroplasty (TVP) and after highly selective vagotomy (HSV).

DATA SOURCES

A search was conducted on MEDLINE with the keywords "peptic ulcer" and "vagotomy". Bibliographics of the articles retrieved and review articles pertaining to the subject were scanned further.

STUDY SELECTION

Included were only published prospective, randomized controlled trials comparing TVP and HSV in the English-language literature up to April 1991. Twelve studies were found.

DATA EXTRACTION

Two authors, working independently, abstracted raw data on mortality, recurrence, dumping, diarrhea and postoperative Visick grading.

DATA SYNTHESIS

A ratio greater than 1.0 indicates a higher proportion occurring with TVP and less than 1.0 a higher proportion with HSV. [Table: See Text]

CONCLUSION

The results suggest that the likelihood of adverse long-term sequelae is higher with TVP whereas the likelihood of recurrence is higher with HSV.

Authors+Show Affiliations

Department of Surgery, University of Toronto, Ont.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Meta-Analysis

Language

eng

PubMed ID

7982148

Citation

Chan, V M., et al. "Meta-analysis of Highly Selective Vagotomy Versus Truncal Vagotomy and Pyloroplasty in the Surgical Treatment of Uncomplicated Duodenal Ulcer." Canadian Journal of Surgery. Journal Canadien De Chirurgie, vol. 37, no. 6, 1994, pp. 457-64.
Chan VM, Reznick RK, O'Rourke K, et al. Meta-analysis of highly selective vagotomy versus truncal vagotomy and pyloroplasty in the surgical treatment of uncomplicated duodenal ulcer. Can J Surg. 1994;37(6):457-64.
Chan, V. M., Reznick, R. K., O'Rourke, K., Kitchens, J. M., Lossing, A. G., & Detsky, A. S. (1994). Meta-analysis of highly selective vagotomy versus truncal vagotomy and pyloroplasty in the surgical treatment of uncomplicated duodenal ulcer. Canadian Journal of Surgery. Journal Canadien De Chirurgie, 37(6), 457-64.
Chan VM, et al. Meta-analysis of Highly Selective Vagotomy Versus Truncal Vagotomy and Pyloroplasty in the Surgical Treatment of Uncomplicated Duodenal Ulcer. Can J Surg. 1994;37(6):457-64. PubMed PMID: 7982148.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Meta-analysis of highly selective vagotomy versus truncal vagotomy and pyloroplasty in the surgical treatment of uncomplicated duodenal ulcer. AU - Chan,V M, AU - Reznick,R K, AU - O'Rourke,K, AU - Kitchens,J M, AU - Lossing,A G, AU - Detsky,A S, PY - 1994/12/1/pubmed PY - 1994/12/1/medline PY - 1994/12/1/entrez SP - 457 EP - 64 JF - Canadian journal of surgery. Journal canadien de chirurgie JO - Can J Surg VL - 37 IS - 6 N2 - OBJECTIVE: To compare critically by meta-analysis the postoperative outcomes after truncal vagotomy and pyloroplasty (TVP) and after highly selective vagotomy (HSV). DATA SOURCES: A search was conducted on MEDLINE with the keywords "peptic ulcer" and "vagotomy". Bibliographics of the articles retrieved and review articles pertaining to the subject were scanned further. STUDY SELECTION: Included were only published prospective, randomized controlled trials comparing TVP and HSV in the English-language literature up to April 1991. Twelve studies were found. DATA EXTRACTION: Two authors, working independently, abstracted raw data on mortality, recurrence, dumping, diarrhea and postoperative Visick grading. DATA SYNTHESIS: A ratio greater than 1.0 indicates a higher proportion occurring with TVP and less than 1.0 a higher proportion with HSV. [Table: See Text] CONCLUSION: The results suggest that the likelihood of adverse long-term sequelae is higher with TVP whereas the likelihood of recurrence is higher with HSV. SN - 0008-428X UR - https://www.unboundmedicine.com/medline/citation/7982148/Meta_analysis_of_highly_selective_vagotomy_versus_truncal_vagotomy_and_pyloroplasty_in_the_surgical_treatment_of_uncomplicated_duodenal_ulcer_ DB - PRIME DP - Unbound Medicine ER -