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[Study on nocturnal penile tumescence (NPT) in healthy males. Study on the relationship between the serum free testosterone level and NPT].
Nihon Hinyokika Gakkai Zasshi. 1994 Oct; 85(10):1511-20.NH

Abstract

We studied the correlation of nocturnal penile tumescence (NPT) and serum free testosterone, which were evaluated in 123 healthy males and in 6 cases of primary hypogonadotropic hypogonadism before and after treatment with human chorionic gonadotropin (hCG). In healthy subjects 3 to 84 years old, the serum free testosterone levels had a relationship with 4 parameters revealed by NPT: total tumescence time, mean tumescence time, maximum penile circumference change and maximum increase rate in penile circumference. In men who showed the peak value for each NPT parameter and those who were younger, the serum free testosterone levels were correlated with all 6 parameters revealed by NPT: total tumescence time, NPT frequency, mean tumescence time, circumference in flaccid penis, maximum penile circumference change and maximum increase rate in penile circumference. In 6 cases of the primary hypogonadotropic hypogonadism, total tumescence time, mean tumescence time, maximum penile circumference change, and maximum increase rate in penile circumference significantly increased after hCG treatment. This indicated that an increase of the serum free testosterone level was responsible for the increase of the parameters of NPT. In men who were older than the subjects showing the peak value for each NPT parameter, the serum free testosterone levels were correlated with 4 parameters revealed by NPT: total tumescence time, mean tumescence time, maximum penile circumference change and maximum increase rate in penile circumference. These results suggest that the free testosterone level may be involved in the decrease of maximum penile circumference change as well as in age-related changes of the penile vascular system that were the major factor responsible for the decrease. This is the first report that studied the relationship between NPT and androgen in any group. NPT as a parameter for the erectile function was related to androgen levels.

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Authors+Show Affiliations

Horita H
Department of Urology, School of Medicine, Sapporo Medical University, Japan.
Kumamoto Y
No affiliation info available

MeSH

AdolescentAdultAgedAged, 80 and overChildChild, PreschoolCircadian RhythmHumansMaleMiddle AgedPenile ErectionSleepTestosterone

Pub Type(s)

English Abstract
Journal Article

Language

jpn

PubMed ID

7990299

Citation

Horita, H, and Y Kumamoto. "[Study On Nocturnal Penile Tumescence (NPT) in Healthy Males. Study On the Relationship Between the Serum Free Testosterone Level and NPT]." Nihon Hinyokika Gakkai Zasshi. the Japanese Journal of Urology, vol. 85, no. 10, 1994, pp. 1511-20.
Horita H, Kumamoto Y. [Study on nocturnal penile tumescence (NPT) in healthy males. Study on the relationship between the serum free testosterone level and NPT]. Nihon Hinyokika Gakkai Zasshi. 1994;85(10):1511-20.
Horita, H., & Kumamoto, Y. (1994). [Study on nocturnal penile tumescence (NPT) in healthy males. Study on the relationship between the serum free testosterone level and NPT]. Nihon Hinyokika Gakkai Zasshi. the Japanese Journal of Urology, 85(10), 1511-20.
Horita H, Kumamoto Y. [Study On Nocturnal Penile Tumescence (NPT) in Healthy Males. Study On the Relationship Between the Serum Free Testosterone Level and NPT]. Nihon Hinyokika Gakkai Zasshi. 1994;85(10):1511-20. PubMed PMID: 7990299.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Study on nocturnal penile tumescence (NPT) in healthy males. Study on the relationship between the serum free testosterone level and NPT]. AU - Horita,H, AU - Kumamoto,Y, PY - 1994/10/1/pubmed PY - 1994/10/1/medline PY - 1994/10/1/entrez SP - 1511 EP - 20 JF - Nihon Hinyokika Gakkai zasshi. The japanese journal of urology JO - Nihon Hinyokika Gakkai Zasshi VL - 85 IS - 10 N2 - We studied the correlation of nocturnal penile tumescence (NPT) and serum free testosterone, which were evaluated in 123 healthy males and in 6 cases of primary hypogonadotropic hypogonadism before and after treatment with human chorionic gonadotropin (hCG). In healthy subjects 3 to 84 years old, the serum free testosterone levels had a relationship with 4 parameters revealed by NPT: total tumescence time, mean tumescence time, maximum penile circumference change and maximum increase rate in penile circumference. In men who showed the peak value for each NPT parameter and those who were younger, the serum free testosterone levels were correlated with all 6 parameters revealed by NPT: total tumescence time, NPT frequency, mean tumescence time, circumference in flaccid penis, maximum penile circumference change and maximum increase rate in penile circumference. In 6 cases of the primary hypogonadotropic hypogonadism, total tumescence time, mean tumescence time, maximum penile circumference change, and maximum increase rate in penile circumference significantly increased after hCG treatment. This indicated that an increase of the serum free testosterone level was responsible for the increase of the parameters of NPT. In men who were older than the subjects showing the peak value for each NPT parameter, the serum free testosterone levels were correlated with 4 parameters revealed by NPT: total tumescence time, mean tumescence time, maximum penile circumference change and maximum increase rate in penile circumference. These results suggest that the free testosterone level may be involved in the decrease of maximum penile circumference change as well as in age-related changes of the penile vascular system that were the major factor responsible for the decrease. This is the first report that studied the relationship between NPT and androgen in any group. NPT as a parameter for the erectile function was related to androgen levels. SN - 0021-5287 UR - https://www.unboundmedicine.com/medline/citation/7990299/[Study_on_nocturnal_penile_tumescence__NPT__in_healthy_males__Study_on_the_relationship_between_the_serum_free_testosterone_level_and_NPT]_ L2 - https://joi.jlc.jst.go.jp/JST.Journalarchive/jpnjurol1989/85.1511?lang=en&from=PubMed DB - PRIME DP - Unbound Medicine ER -