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[Importance of prolactin isoforms on ovary function in hyperprolactinemic women].
Rev Chil Obstet Ginecol. 1993; 58(6):465-9.RC

Abstract

Gel filtration chromatography in Sephadex G-100, was used to analyse the molecular heterogeneity of prolactin (PRL) in serum from seven hyperprolactinemic women. Chromatographic patterns from samples obtained from four women with hyperprolactinemia and normal menstrual cycles showed a predominance of big-big PRL (79%). In contrast, three women with hyperprolactinemia and amenorrhea presented a chromatographic pattern with predominance of little PRL (69%). The results suggest that the molecular heterogeneity of PRL found is associated with menstrual cycles disorders and hence with ovarian function. Normal ovarian function in hyperprolactinemic patients seems to be associated to increased levels of big-big PRL and altered ovarian function to high level of little PRL.

Authors+Show Affiliations

Departamento de Obstetricia y Ginecología, Hospital J.J. Aguirre, Universidad de Chile.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

spa

PubMed ID

7991872

Citation

Romero, C, et al. "[Importance of Prolactin Isoforms On Ovary Function in Hyperprolactinemic Women]." Revista Chilena De Obstetricia Y Ginecologia, vol. 58, no. 6, 1993, pp. 465-9.
Romero C, León J, Jara R, et al. [Importance of prolactin isoforms on ovary function in hyperprolactinemic women]. Rev Chil Obstet Ginecol. 1993;58(6):465-9.
Romero, C., León, J., Jara, R., & González, O. (1993). [Importance of prolactin isoforms on ovary function in hyperprolactinemic women]. Revista Chilena De Obstetricia Y Ginecologia, 58(6), 465-9.
Romero C, et al. [Importance of Prolactin Isoforms On Ovary Function in Hyperprolactinemic Women]. Rev Chil Obstet Ginecol. 1993;58(6):465-9. PubMed PMID: 7991872.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Importance of prolactin isoforms on ovary function in hyperprolactinemic women]. AU - Romero,C, AU - León,J, AU - Jara,R, AU - González,O, PY - 1993/1/1/pubmed PY - 1993/1/1/medline PY - 1993/1/1/entrez SP - 465 EP - 9 JF - Revista chilena de obstetricia y ginecologia JO - Rev Chil Obstet Ginecol VL - 58 IS - 6 N2 - Gel filtration chromatography in Sephadex G-100, was used to analyse the molecular heterogeneity of prolactin (PRL) in serum from seven hyperprolactinemic women. Chromatographic patterns from samples obtained from four women with hyperprolactinemia and normal menstrual cycles showed a predominance of big-big PRL (79%). In contrast, three women with hyperprolactinemia and amenorrhea presented a chromatographic pattern with predominance of little PRL (69%). The results suggest that the molecular heterogeneity of PRL found is associated with menstrual cycles disorders and hence with ovarian function. Normal ovarian function in hyperprolactinemic patients seems to be associated to increased levels of big-big PRL and altered ovarian function to high level of little PRL. SN - 0048-766X UR - https://www.unboundmedicine.com/medline/citation/7991872/[Importance_of_prolactin_isoforms_on_ovary_function_in_hyperprolactinemic_women]_ DB - PRIME DP - Unbound Medicine ER -
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