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Some biochemical and pharmacological aspects of free radical-mediated tissue damage.

Abstract

Living in aerobic conditions carries a risk of oxidative stress, in connection with free radical deleterious action on tissues and cells. Free radical mechanisms have been implicated in the pathogenesis of many diseases, as well as in host defense against various invading microorganisms. A substantial body of evidence has been reported on free radical involvement in inflammation, ischaemia/reperfusion injury, atherosclerosis and many other pathologies. The aim of this paper is to review selected literature and opinions concerning free radical-induced damage to tissues and to present xenobiotic contribution to oxidative stress.

Authors+Show Affiliations

,

K. Marcinkowski Medical Academy, Poznań, Poland.

Source

MeSH

Aging
Antioxidants
Arteriosclerosis
Arthritis, Rheumatoid
Carcinogens
Free Radicals
Humans
In Vitro Techniques
Inflammation
Neoplasms
Oxidative Stress
Reactive Oxygen Species
Reperfusion Injury

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

8000441

Citation

Ignatowicz, E, and M Rybczyńska. "Some Biochemical and Pharmacological Aspects of Free Radical-mediated Tissue Damage." Polish Journal of Pharmacology, vol. 46, no. 3, 1994, pp. 103-14.
Ignatowicz E, Rybczyńska M. Some biochemical and pharmacological aspects of free radical-mediated tissue damage. Pol J Pharmacol. 1994;46(3):103-14.
Ignatowicz, E., & Rybczyńska, M. (1994). Some biochemical and pharmacological aspects of free radical-mediated tissue damage. Polish Journal of Pharmacology, 46(3), pp. 103-14.
Ignatowicz E, Rybczyńska M. Some Biochemical and Pharmacological Aspects of Free Radical-mediated Tissue Damage. Pol J Pharmacol. 1994;46(3):103-14. PubMed PMID: 8000441.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Some biochemical and pharmacological aspects of free radical-mediated tissue damage. AU - Ignatowicz,E, AU - Rybczyńska,M, PY - 1994/5/1/pubmed PY - 1994/5/1/medline PY - 1994/5/1/entrez SP - 103 EP - 14 JF - Polish journal of pharmacology JO - Pol J Pharmacol VL - 46 IS - 3 N2 - Living in aerobic conditions carries a risk of oxidative stress, in connection with free radical deleterious action on tissues and cells. Free radical mechanisms have been implicated in the pathogenesis of many diseases, as well as in host defense against various invading microorganisms. A substantial body of evidence has been reported on free radical involvement in inflammation, ischaemia/reperfusion injury, atherosclerosis and many other pathologies. The aim of this paper is to review selected literature and opinions concerning free radical-induced damage to tissues and to present xenobiotic contribution to oxidative stress. SN - 1230-6002 UR - https://www.unboundmedicine.com/medline/citation/8000441/Some_biochemical_and_pharmacological_aspects_of_free_radical_mediated_tissue_damage_ L2 - https://www.lens.org/lens/search?q=citation_id:8000441 DB - PRIME DP - Unbound Medicine ER -