TY - JOUR T1 - Clinical epidemiological study of 171 cases of cryptococcosis. AU - Rozenbaum,R, AU - Gonçalves,A J, PY - 1994/3/1/pubmed PY - 1994/3/1/medline PY - 1994/3/1/entrez SP - 369 EP - 80 JF - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America JO - Clin Infect Dis VL - 18 IS - 3 N2 - We retrospectively studied 171 patients with cryptococcosis who were divided into three groups according to their associated predisposing conditions (if any): group 1 comprised nonimmunosuppressed patients, group 2 comprised patients with AIDS, and group 3 comprised those patients with other conditions and/or who were users of immunosuppressive drugs. Analysis and correlation of the behavior of the mycosis among the three groups showed differences in the demographic data, clinical forms and manifestations of cryptococcosis, laboratory results, morbidity and mortality rates, and histopathologic aspects. Study of the clinical isolates of Cryptococcus neoformans from 83 patients with cryptococcosis showed that 75 were characterized as C. neoformans variety neoformans and eight as C. neoformans var. gatti. Comparison of the distribution of the gattii and neoformans varieties between the nonimmunosuppressed (group 1) and immunosuppressed (groups 2 and 3) patients showed a significant statistical difference (P < .01). SN - 1058-4838 UR - https://www.unboundmedicine.com/medline/citation/8011818/Clinical_epidemiological_study_of_171_cases_of_cryptococcosis_ L2 - https://academic.oup.com/cid/article-lookup/doi/10.1093/clinids/18.3.369 DB - PRIME DP - Unbound Medicine ER -