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[Imerslund-Najman-Grasbeck anemia. Apropos of a case].
Pediatrie. 1993; 48(10):693-5.P

Abstract

Imerslund-Najman-Grasbeck disease is a rare inherited megaloblastic anaemia secondary to a selective malabsorption of vitamin B12 by ileal enterocytes. The authors report on a 4 year-old tunisian girl who presented as visceral infantile leishmaniasis because of huge splenomegaly and major anaemia. The diagnosis of Imerslund disease was performed on the basis of the association of typical megaloblastic cells in the marrow, permanent proteinuria and favourable outcome under parenteral B12 administration. In addition, ther were no folate deficiency, no anti-intrinsic factor antibodies and no intrinsic factor deficiency. The outcome of the disease is always favourable if parenteral administration of vitamin B12 maintained.

Authors+Show Affiliations

Service de pédiatrie de Mahdia, Tunisie.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

fre

PubMed ID

8015868

Citation

Ben Meriem, C, et al. "[Imerslund-Najman-Grasbeck Anemia. Apropos of a Case]." Pediatrie, vol. 48, no. 10, 1993, pp. 693-5.
Ben Meriem C, Pousse H, Bourgeay-Causse M, et al. [Imerslund-Najman-Grasbeck anemia. Apropos of a case]. Pediatrie. 1993;48(10):693-5.
Ben Meriem, C., Pousse, H., Bourgeay-Causse, M., Amri, F., Besbes, A., Belkhir, A., Sfar, M. T., & Jrad, T. (1993). [Imerslund-Najman-Grasbeck anemia. Apropos of a case]. Pediatrie, 48(10), 693-5.
Ben Meriem C, et al. [Imerslund-Najman-Grasbeck Anemia. Apropos of a Case]. Pediatrie. 1993;48(10):693-5. PubMed PMID: 8015868.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Imerslund-Najman-Grasbeck anemia. Apropos of a case]. AU - Ben Meriem,C, AU - Pousse,H, AU - Bourgeay-Causse,M, AU - Amri,F, AU - Besbes,A, AU - Belkhir,A, AU - Sfar,M T, AU - Jrad,T, PY - 1993/1/1/pubmed PY - 2000/5/5/medline PY - 1993/1/1/entrez SP - 693 EP - 5 JF - Pediatrie JO - Pediatrie VL - 48 IS - 10 N2 - Imerslund-Najman-Grasbeck disease is a rare inherited megaloblastic anaemia secondary to a selective malabsorption of vitamin B12 by ileal enterocytes. The authors report on a 4 year-old tunisian girl who presented as visceral infantile leishmaniasis because of huge splenomegaly and major anaemia. The diagnosis of Imerslund disease was performed on the basis of the association of typical megaloblastic cells in the marrow, permanent proteinuria and favourable outcome under parenteral B12 administration. In addition, ther were no folate deficiency, no anti-intrinsic factor antibodies and no intrinsic factor deficiency. The outcome of the disease is always favourable if parenteral administration of vitamin B12 maintained. SN - 0031-4021 UR - https://www.unboundmedicine.com/medline/citation/8015868/[Imerslund_Najman_Grasbeck_anemia__Apropos_of_a_case]_ L2 - http://www.diseaseinfosearch.org/result/441 DB - PRIME DP - Unbound Medicine ER -